This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Hepatitis B Vaccine contains an active agent as Hepatitis B Injection (rDNA). It is used to protect against hepatitis B virus infection in children. This vaccine also protects children from hepatic cellular carcinoma (liver cancer). Hepatitis B virus is a virus that damages the liver and gradually stops the liver from working properly. Hepatitis B Vaccine is especially advantageous for babies with neuro disorders. This vaccine also allows normal immunization for preterm (born too early) and low birth weight infants, which otherwise might be delayed.

The first hepatitis B vaccine was approved by the US Food and Drug Administration (FDA) in 1981. Since then, several vaccine versions have been developed and approved by the FDA for use in the United States. The most recent approval was in November 2017, when the FDA approved a two-dose hepatitis B vaccine for adults called HEPLISAV-B.

Mechanism of Action of undefined

The effect of the Hepatitis B Vaccine is its ability to provide protection against the hepatitis B virus (HBV) and prevent the development of hepatitis B infection. When a person is vaccinated against hepatitis B, their immune system produces antibodies that can recognize and neutralize the virus. This means that if they are later exposed to HBV, their immune system can quickly respond and prevent the virus from causing an infection.

Uses of undefined

Hepatitis B Vaccine is used to prevent Hepatitis B virus infection.

undefined Drug administaration and Dosage available

The Hepatitis B Vaccine is administered as an injection into the upper arm. The specific dosage and number of injections required can vary depending on the individual's age and vaccination history. For infants, the vaccine is typically given in three doses, with the first dose administered at birth or shortly after that and the second and third doses given at 1-2 months and six months of age.

Warnings, Precautions and Side Effects of undefined


Rare instances of severe allergic reactions and neurological disorders have been reported with the hepatitis B vaccine. Individuals who are pregnant or have weakened immune systems should discuss the risks and benefits of vaccination with their healthcare provider. Other warnings include the possibility of fainting, shoulder injury related to vaccine administration, and the potential for the vaccine to interact with other medications. 


Individuals with a history of severe allergic reactions to any Hepatitis B Vaccine component should not receive it. A person should disclose medical conditions or allergies to a healthcare provider before receiving the vaccine. After vaccination, it is recommended to remain at the healthcare facility for some time to monitor for any immediate adverse reactions and to report any delayed or persistent symptoms to your healthcare provider.

Side Effects

The hepatitis B vaccine is generally considered safe, with most people experiencing no or only mild side effects. Common side effects may include pain, redness or swelling at the injection site, headache, fever, fatigue, and muscle aches. Serious side effects such as severe allergic reactions and neurological disorders are rare.

Word Of Advice

If you are considering getting the Hepatitis B Vaccine, it is important to be aware of the potential risks and warnings associated with the vaccine. Individuals who are pregnant or have weakened immune systems should discuss the risks and benefits of vaccination with their healthcare provider. The vaccine may not be as effective in individuals with weakened immune systems, such as those with HIV or those undergoing chemotherapy. It is important to understand that the benefits of vaccination in preventing hepatitis B infection and associated liver diseases far outweigh any potential risks, and getting vaccinated is an important step in protecting your health.

Frequently Asked Question


  1. Bharat Biotech, [Revised on July 2019] [Accessed on 9th May 2023],
  2. GlaxoSmithKline, Electronic medicines compendium (EMC), [Revised on May 2020] [ Accessed on 9th May 2023],
  3. KD Tripathi, Essentials of Medical Pharmacology, Vaccines and sera, 7th edition, 2013, 923.


The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.