This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Human Albumin Injection is an albumin solution for injection which was approved by the US Food and Drug Administration for its medical use on 4th August 2014.

Mechanism of Action of undefined

The main mechanism of action of Human Albumin Injection is to increase the colloidal osmotic pressure. It reduces fluid accumulation by pulling the fluid from the intravascular space and increases circulatory blood volume.

Uses of undefined

Human Albumin Injection has been developed to treat hypovolemia, hypoalbuminemia, cardiopulmonary bypass surgery and hemolytic disease of the new born.

undefined Drug administaration and Dosage available

Human Albumin is available as 5% and 20% solution for injection. Human Albumin Injection is administered as an intravenous infusion. Your physician will calculate the accurate dose based on your health status and body weight.

For infants and young children with Hypovolemic shock, the ideal dose is 2.5 to 5 ml per kg body weight whereas for older children and adults, the ideal dose is 100 to 200 ml. For patients with hypoalbuminemia, the dose is 80 to 100 ml per kg body weight. for hemolytic disease of newborn, 1 gram per kg body weight is administered before or during exchange transfusion.

Warnings, Precautions and Side Effects of undefined

Warnings

Contact your doctor immediately if you experience shortness of breath, fever, or severe bleeding. During the Human Albumin Injection treatment, your doctor may periodically monitor your white blood cell counts, platelets, blood clotting factors, blood sugar, electrolytes and kidney parameters to prevent serious complications. Report to your doctor if you have been diagnosed with heart failure, hypertension, esophageal varices, pulmonary edema, bleeding problems, severe anaemia or kidney disease. Get immediate medical attention if you have any allergies, headache or breathing trouble as these signs indicate heart trouble.

Precautions

It is not known whether Human Albumin Injection causes fetal harm or passes into the breast milk. However, it is advisable to tell your healthcare practitioner before starting this treatment if you are pregnant, breastfeeding or planning to have a baby.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Human Albumin Injection are headache, vomiting, nausea, rash, pruritus, fever, chills, low BP and flushing. Hypersensitivity, pulmonary edema, rapid heart rate and breathlessness are some of the severe adverse reactions of Human Albumin Injection and you should report to your healthcare provider right away if you experience any of these symptoms.

Word Of Advice

It is advisable to monitor your blood pressure regularly during this treatment. If you experience dizziness or any visual disturbances, you should avoid driving or handling machines. Apply cool compress at the injection site to reduce the pain.

Frequently Asked Question

References

  1. Baxalta US Inc., US Food & Drug Administration, [Revised on Aug 2019] [Accessed on 25th Aug 2022], https://www.fffenterprises.com/assets/downloads/pi-Albumin-PPF_FLEXBUMIN%2025_Baxter.pdf
  2. Campos Munoz A, Jain NK, Gupta M. Albumin Colloid. [Updated 2022 Jun 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan, [Accessed on 25th Aug 2022], https://www.ncbi.nlm.nih.gov/books/NBK534241/

Disclaimer

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.