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Author Details
Written By
P. Thirumal Reddy
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 23 Jun 2026 | 07:03 AM (IST)
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Quick Summary
HUMAN ALBUMIN
Last updated on 23 Jun 2026 | 07:03 AM (IST)
HUMAN ALBUMIN
Background and Date of approval HUMAN ALBUMIN
Human Albumin Injection is an albumin solution for injection which was approved by the US Food and Drug Administration for its medical use on 4th August 2014.
Uses of HUMAN ALBUMIN
Human Albumin Injection has been developed to treat hypovolemia, hypoalbuminemia, cardiopulmonary bypass surgery and hemolytic disease of the new born.
How is HUMAN ALBUMIN administered?
Human Albumin is available as 5% and 20% solution for injection. Human Albumin Injection is administered as an intravenous infusion. Your physician will calculate the accurate dose based on your health status and body weight.
For infants and young children with Hypovolemic shock, the ideal dose is 2.5 to 5 ml per kg body weight whereas for older children and adults, the ideal dose is 100 to 200 ml. For patients with hypoalbuminemia, the dose is 80 to 100 ml per kg body weight. for hemolytic disease of newborn, 1 gram per kg body weight is administered before or during exchange transfusion.
Side Effects of HUMAN ALBUMIN
The common side effects that are likely to occur while you are on the treatment with Human Albumin Injection are headache, vomiting, nausea, rash, pruritus, fever, chills, low BP and flushing. Hypersensitivity, pulmonary edema, rapid heart rate and breathlessness are some of the severe adverse reactions of Human Albumin Injection and you should report to your healthcare provider right away if you experience any of these symptoms.
Warnings
Contact your doctor immediately if you experience shortness of breath, fever, or severe bleeding. During the Human Albumin Injection treatment, your doctor may periodically monitor your white blood cell counts, platelets, blood clotting factors, blood sugar, electrolytes and kidney parameters to prevent serious complications. Report to your doctor if you have been diagnosed with heart failure, hypertension, esophageal varices, pulmonary edema, bleeding problems, severe anaemia or kidney disease. Get immediate medical attention if you have any allergies, headache or breathing trouble as these signs indicate heart trouble.
Precautions
It is not known whether Human Albumin Injection causes fetal harm or passes into the breast milk. However, it is advisable to tell your healthcare practitioner before starting this treatment if you are pregnant, breastfeeding or planning to have a baby.
Word of Advice
It is advisable to monitor your blood pressure regularly during this treatment. If you experience dizziness or any visual disturbances, you should avoid driving or handling machines. Apply cool compress at the injection site to reduce the pain.
Frequently Asked Questions
Q1.
How is Human Albumin Injection administered?
Human Albumin Injection is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, age and health status.
Q2.
Is it safe for women of reproductive age to use Human Albumin Injection?
It is not known whether Human Albumin Injection causes fetal harm or passes into the breast milk. However, it is advisable to tell your healthcare practitioner before starting this treatment if you are pregnant, breastfeeding or planning to have a baby.
Q3.
What should you know before using Human Albumin Injection?
It is important to know that you should not dilute albumin solution with sterile water as it may result in haemolysis and acute kidney injury.
Q4.
Who should not use Human Albumin Injection?
People who are hypersensitive to Human Albumin or its ingredients should not use Human Albumin Injection. Human Albumin Injection is also not recommended for people with severe anaemia, heart failure and kidney problem.
Q5.
Will you be monitored during this treatment?
Yes, you will be monitored during Human Albumin treatment. Your healthcare provider will regularly access your blood pressure, heart rate, electrolytes and your complete blood count.
Q6.
What are the early signs of hypersensitivity reactions?
Hives, generalized urticaria, chest tightness, breathlessness, wheezing, low BP, and faintness are some of the most common early signs of hypersensitivity reactions.
Q7.
How to store Human Albumin Injection?
Store Human Albumin Injection at room temperature (below 30°C) and use immediately once opened. Discard unused portion after administration.
References
- Baxalta US Inc., US Food & Drug Administration, [Revised on Aug 2019] [Accessed on 25th Aug 2022], https://www.fffenterprises.com/assets/downloads/pi-Albumin-PPF_FLEXBUMIN%2025_Baxter.pdf
- Campos Munoz A, Jain NK, Gupta M. Albumin Colloid. [Updated 2022 Jun 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan, [Accessed on 25th Aug 2022], https://www.ncbi.nlm.nih.gov/books/NBK534241/
Disclaimer
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.
