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Written By
P. Thirumal Reddy
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 12 Aug 2026 | 06:30 AM (IST)

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HEPATITIS B IMMUNOGLOBULIN VACCINE
Last updated on 12 Aug 2026 | 06:30 AM (IST)
HEPATITIS B IMMUNOGLOBULIN VACCINE
Background and Date of approval HEPATITIS B IMMUNOGLOBULIN VACCINE
The U.S. FDA-approved Human Hepatitis B immunoglobulin to treat people protected from the hepatitis B virus on January 30, 2006. It is usually given with the hepatitis B vaccine.
Uses of HEPATITIS B IMMUNOGLOBULIN VACCINE
Human Hepatitis B immunoglobulin is used in adults and children to protect from the hepatitis B virus, usually given with the hepatitis B vaccine. The Hepatitis B virus damages the liver and gradually stops the liver from working properly. Additionally, this medicine can also be given to newborn babies born to mothers with the hepatitis B virus.
How is HEPATITIS B IMMUNOGLOBULIN VACCINE administered?
Human Hepatitis B immunoglobulin vaccine is administered into a muscle or deep under the skin. If this injection is recommendedThe most common side effects of Human Hepatitis B immunoglobulin are headache, dizziness, Injection site reactions (redness, pain, swelling), joint pain, nausea, fever, skin allergic reaction, low blood pressure
for you, it will be given by a healthcare professional. Do not self-administrate. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Side Effects of HEPATITIS B IMMUNOGLOBULIN VACCINE
Do not take this drug if you are allergic to Human Hepatitis B immunoglobulin and its other ingredients. Before taking the Human Hepatitis B immunoglobulin vaccine, inform your doctor if you have any allergic reaction or a blood disorder (blood clotting) or if you have had kidney dialysis. Notify your doctor if you have IgA deficiency, high blood pressure, or diabetics,
Warnings
Do not take this drug if you are allergic to Human Hepatitis B immunoglobulin and its other ingredients. Before taking the Human Hepatitis B immunoglobulin vaccine, inform your doctor if you have any allergic reaction or a blood disorder (blood clotting) or if you have had kidney dialysis. Notify your doctor if you have IgA deficiency, high blood pressure, or diabetics,
Precautions
Report to your doctor if you recently had any vaccinations or are planning to get any vaccination, especially MMR (measles, mumps, and rubella) vaccine and Varicella (chickenpox) vaccine.
Word of Advice
Store in a refrigerator between 2°C-8°C. Keep away from moisture, heat, and light. Do not freeze the medicine. Keep out of the reach of children and pets. Human Hepatitis B immunoglobulin vaccine is administered into a muscle or deep under the skin. Dosage will be recommended by your physician. Multiple doses may be required to provide adequate protection. Follow the recommended schedule and complete the full course of vaccination as advised by your healthcare provider. Follow the recommended schedule and complete the full course of vaccination as advised by your healthcare provider.
Frequently Asked Questions
Q1.
How long does the Human Hepatitis B immunoglobulin vaccine work in my body?
Human Hepatitis B immunoglobulin vaccine provides long-term protection, but the duration can vary among individuals. This vaccine offers protection for several years, and booster doses may be recommended in certain cases, especially for individuals with compromised immune systems.
Q2.
Can Human Hepatitis B immunoglobulin be given to newborns?
The Human Hepatitis B immunoglobulin vaccine is recommended for newborns. Also, given to infants born to mothers who are infected with hepatitis B.
Q3.
Is Human Hepatitis B immunoglobulin vaccine administrated through the vein?
No, Human Hepatitis B immunoglobulin vaccine is injected into a muscle (intramuscular) or under the skin (subcutaneous).
Q4.
What is the temperature to store Human Hepatitis B immunoglobulin vaccine?
Store in a refrigerator between 2°C-8°C. Also, keep away from the reach of children and pets.
Q5.
Should I get the second dose of Human Hepatitis B immunoglobulin vaccine?
It will be decided by your healthcare professional. Contact your physician if you think that the vaccine is not working in your body.
References
- Bio Products Laboratory Limited, Electronic medicines compendium (emc), [Revised on Dec 2021], [ Accessed on 17th May 2023], https://www.medicines.org.uk/emc/files/pil.5541.pdf
- Cangene biopharma, Inc, US Food and Drug Administration, [Revised on Jan 2012] [ Accessed on 17th May 2023], https://www.fda.gov/media/74701/download
- Shahid Habib, Obaid S Shaikh; Hepatitis B immune globulin; Drugs of Today; Published on June 2007; Accessed on 19/07/2021; https://pubmed.ncbi.nlm.nih.gov/17612709/
Disclaimer
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.






