Human Normal Immunoglobulin is an immunomodulatory agent which was approved for its medical use in 1981.

Human Normal Immunoglobulin Injection has been developed to treat adults with inflammatory disorders, primary and secondary immunodeficiencies.

Human Normal Immunoglobulin is available as a vial containing solution for injection, intended for administration as an intravenous infusion. It is available in the doses 0.5g, 2.5g, 5g, 10g, and 16.5%. The dosing and frequency vary according to the medical condition and bodyweight.

The common side effects that are likely to occur while you are on the treatment with Human Normal Immunoglobulin Injection are headache, nausea, fever, increased heart rate, high blood pressure, chills, musculoskeletal pain, breathlessness and infusion site reactions. If you experience any allergic reactions like chest tightness, wheezing, low BP or urticaria after taking this injection, report to your doctor immediately.

Contact your doctor immediately if you experience sudden weight gain, swelling, urticaria, chest tightness, low urine output, drowsiness, increased heart rate or breathing trouble. During the Human Normal Immunoglobulin injection treatment, your doctor may periodically monitor your blood pressure, blood sugar, electrolytes, serum osmolarity, urine output, heart, liver and kidney parameters to prevent serious complications. Report to your doctor if you have been diagnosed with other autoimmune disorders, depression, seizures, blood disorders or problems in your heart, liver or kidneys. Patients with severe liver and kidney impairment should exercise caution while using this medicine. Do not use this injection if you have experienced allergic reactions to human immunoglobulin.

t is not known if Human Normal Immunoglobulin is safe for to use during pregnancy. Tell your physician before starting this treatment if you are pregnant, think you might be pregnant or planning to have a baby. It is not known if Human Normal Immunoglobulin passes into the breastmilk. However, it is advisable to tell your physician before starting this treatment if you are a breastfeeding mother or planning to breastfeed your child.

Eat a well-balanced diet. If you feel dizzy or tired, you should avoid driving or handling machines. Do not touch or rub your skin after injecting this medicine. Wear a loose-fitting clothing to avoid discomfort.

1. Octapharma USA Inc., US Food & Drug Administration, [Revised on Mar 2022] [Accessed on 10th Oct 2022], https://www.fda.gov/media/70911/download
2. Octapharma AG, Therapeutic Goods Administration, [Revised on Mar 2021] [Accessed on 10th Oct 2022], https://www.tga.gov.au/sites/default/files/auspar-human-normal-immunoglobulin-210621-pi.pdf
3. Novaretti MC, Dinardo CL, Immunoglobulin: production, mechanisms of action and formulations, Rev Bras Hematol Hemoter, 2011, 33(5), 377-82, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415776/pdf/rbhh-33-377.pdf

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.