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Author Details
Written By
P. Thirumal Reddy
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 02 Apr 2026 | 09:48 AM (IST)
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Quick Summary
HYALURONIC ACID
Last updated on 02 Apr 2026 | 09:48 AM (IST)
HYALURONIC ACID
Background and Date of approval HYALURONIC ACID
Hyaluronic acid is a high molecular weight polysaccharide approved for its medical use in 1997.
Uses of HYALURONIC ACID
Hyaluronic acid Injection has been developed to treat symptoms of pain in patients diagnosed with osteoarthritis of the knees who have not responded to conventional treatment methods like painkillers, exercise, and physical therapy. This injection improves mobility and enhances joint function.
How is HYALURONIC ACID administered?
A healthcare professional will administer Hyaluronic acid as an intraarticular injection to the patients. The dose will depend on the patient’s severity of the condition. Hyaluronic Acid is available as a prefilled syringe in the doses 20mg and 60mg. Your healthcare provider will inject this medicine directly into the affected joint.
Side Effects of HYALURONIC ACID
Although there are no significant side effects of Hyaluronic acid, one might notice a flare up within 24 hours of administering this injection, which settles within two days. If you experience any allergic reactions such as anaphylaxis or infection, report to your doctor immediately.
Warnings
Contact your doctor immediately if you experience infections or allergies. Report to your doctor if you have skin problems or infections near the affected joint. Tell your healthcare provider before receiving this injection if you have been diagnosed with bleeding disorders.
Precautions
It is not known whether hyaluronic acid interferes with pregnancy or breastfeeding. Tell your healthcare provider before starting treatment with Hyaluronic acid if you are pregnant, breastfeeding you baby, think you might be pregnant or planning to have a baby.
Word of Advice
Hyaluronic acid is not known to interfere with your ability to drive or operate machines. Avoid doing activities that cause strain on your joints for at least two days after taking this injection.
Frequently Asked Questions
Q1.
When should you not take Hyaluronic Acid Injection?
You should avoid taking Hyaluronic Acid Injection if you have a history of hypersensitivity reaction to hyaluronic acid, egg, poultry or other ingredients. Avoid injecting Hyaluronic Acid if the skin around the affected part is infected or injured.
Q2.
Is it safe to use Hyaluronic acid during pregnancy and breastfeeding?
It is not known whether hyaluronic acid interferes with pregnancy or breastfeeding. Tell your healthcare provider before starting treatment with Hyaluronic acid if you are pregnant, breastfeeding you baby, think you might be pregnant or planning to have a baby.
Q3.
What should you avoid doing after taking Hyaluronic acid Injection?
It is recommended to avoid activities like jogging, sports, weight lifting, and standing on your feet for a long time while on treatment with Hyaluronic acid.
Q4.
Can you take other medications along with Hyaluronic Acid?
Yes, you can take other medications along with Hyaluronic acid as this medication is not known to interfere with other treatments. However, tell your healthcare provider or physiotherapist before taking Hyaluronic acid if you are taking blood thinning medications like warfarin.
Q5.
How is Hyaluronic acid administered?
Your healthcare provider will administer Hyaluronic acid Injection through intra articular route, directly into your affected joint.
Q6.
How long does it take to experience results?
Hyaluronic Acid Injection typically takes around a week to experience a reduction in pain. However, the results vary according to your severity of pain and pre-existing medical conditions.Â
Q7.
How long do the benefits of Hyaluronic Acid Injection last?
The duration of effect varies according to the individual. Usually, your healthcare provider will recommend three to five doses of Hyaluronic Acid Injection at weekly intervals that can provide adequate relief for about 6 months.Â
References
1. Kendra Walker, Brandon M. Basehore, Amandeep Goyal, Patrick M. Zito, Hyaluronic Acid, StatPearls [Internet], [Revised on Jul 2022] [Accessed on 14th Sep 2022], https://www.ncbi.nlm.nih.gov/books/NBK482440/
2. Hyalgan Patient Information, [Accessed on 14th Sep 2022], https://www.hyalgan.com/wp-content/uploads/2016/05/HyalganPatInfoPDFupdate513.pdf
3. Hyaluronic Acid (HA) Injection, Patient Information Leaflet, [Accessed on 14th Sep 2022], https://www.ultrasound-guided-injections.co.uk/wp-content/uploads/2018/02/Hyaluronic-acid-HA-injection-patient-info-leaflet.pdfÂ
Disclaimer
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.
