Hyaluronic acid, lidocaine hydrochloride was approved by US Food and drug administration for the indication to treat Hyaluronic acid as an anti-wrinkle agent. It is a moisturizer that helps to stretch the skin and reduce wrinkles and lines. Lidocaine belongs to a group of local anesthetics. 

Hyaluronic acid, lidocaine hydrochloride is used to treat moderate to severe facial wrinkles, nasolabial folds in skin, lip augmentation, correction of perioral lines, and improves under eye hollows.

Hyaluronic acid, lidocaine hydrochloride is available as an injectable gel dosage form. This medicine is given only in a hospital setup by a healthcare provider. Hyaluronic acid, lidocaine hydrochloride will be given to you by your doctor. It is given subcutaneous injection, either as a single injection or as a continuous infusion (a drip). Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors. 

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common side effects may include redness, swelling, pain, tenderness, firmness,  lumps/bumps,  bruising,  discoloration and itching.  Keep an eye out for these signs and contact your doctor immediately if you experience any of them while receiving therapy.

It is not recommended to take this medication if you are allergic to the active substance Hyaluronic acid, lidocaine hydrochloride and its components. Proper injection technique is essential to ensure optimal results and minimize complications. Only trained and qualified healthcare providers should administer injections of hyaluronic acid with lidocaine hydrochloride. Tell your physician about all the medications you have been taking recently before starting treatment.

The safety and efficacy of hyaluronic acid + lidocaine hydrochloride have not been studied for individuals under 18 years of age. So, it is recommended to consult your doctor or dermatologist before using it. Speak with your doctor if you plan to do laser treatments or a chemical peel or under any medication like chemotherapy/ immunotherapy before starting to use it. Don't use makeup for 12 hours after the treatment and minimize vigorous exercise exposure to sun or heat after using the drug.

It is recommended to inform your doctor if you have a brain, blood, respiratory, or kidney disorder before using the medicine. Consult your doctor if you have a fever before taking the medicine. inform your doctor as soon as possible if you have difficulty breathing, blueness of the tongue or lips, rash, swelling of the face or throat, sudden and serious malaise with a reduction in blood pressure leads to dizziness and loss of consciousness, accelerated heart rate associated with respiratory disorders. 

1. Juvéderm, Manufacturer, [Accessed on 4th Nov 2023], https://www.juvederm.com/
2. Roberto Tinoco and James E. Crowe, Jr., Immunoglobulins and Vaccines, Goodman & Gilman's The Pharmacological Basis of Therapeutics, 13th Edition, 2018, 655-672.

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.