The U.S. FDA approved Ibandronic Acid as an anti-resorptive medication to treat Osteoporosis and hypercalcemia on 16th May 2003.

Ibandronic Acid has been developed to treat osteoporosis and prevent bone complications in patients diagnosed with bone cancer. A condition called tumor-induced hypercalcemia is common among people diagnosed with cancer. Ibandronic acid reduces blood calcium levels in such conditions.

Ibandronic Acid Injection

Ibandronic Acid is available as a single-dose vial for injection in the dose 6mg and as tablets in the doses 50mg and 150mg. The injection is intended for administration as an intravenous infusion after reconstitution every 4 weeks. Your healthcare provider will prescribe an accurate dose depending on your health condition. If you have been diagnosed with a kidney problem, your doctor will administer a lower dose.  

Ibandronic Acid Tablet

Ibandronic acid tablet is usually taken once a month with a glass of water. Avoid chewing, breaking, or crushing it. Do not lie down immediately after taking this medicine. If this medicine is prescribed, your physician will choose the dosage based on your medical condition because it differs for each person.

The common side effects that are likely to occur while you are on the treatment with Ibandronic Acid are low levels of calcium, headache, flu, tiredness, weakness, flatulence, chills, muscle pain, nausea, vomiting, back pain and diarrhea. If you experience any reactions like rashes, bruising, swelling, and itching at the Injection site, report to your doctor immediately.

During the Ibandronic Acid Injection treatment, your doctor may periodically monitor your blood calcium, phosphorus and magnesium and kidney parameters to prevent serious complications. Get a dental appointment before starting treatment with Ibandronic Acid Injection. Tell your healthcare provider before starting treatment with Ibandronic Acid Injection if you have been diagnosed with hypocalcemia, a problem in your heart or kidneys, or you are undergoing chemotherapy/radiotherapy. Get immediate medical attention if you have dizziness, severe nausea/vomiting, breathlessness or severe stomach ache. 

Ibandronic Acid Injection is not recommended for use during pregnancy and breastfeeding. Tell your healthcare provider before starting this treatment if you are pregnant, think you might be pregnant, breastfeeding, or planning to have a baby.

Ibandronic Acid Injection rarely causes dizziness and sickness. However, it is advisable to avoid driving or handling machines during this treatment if you feel uncomfortable. Drink sufficient water before treatment to prevent dehydration. 

1. KD Tripathi, Hormones and Drugs Affecting Calcium Balance, Essentials of Medical Pharmacology, 8th Edition, 2019, 360-372.
2. Apotex Inc., [Revised on Feb 2017] [Accessed on 12th Oct 2022], https://www.apotex.com/products/us/downloads/pre/iban_imtb_ins.pdf
3. Atnahs Pharma Australia Pty Ltd., [Revised on Oct 2018] [Accessed on 12th Oct 2022], https://secure.guildlink.com.au/gc/ws/iy/pi.cfm?product=iypbondr

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.