This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
The U.S. FDA-approved Idelalisib to treat people with chronic lymphocytic leukemia (CLL) and follicular lymphoma on July 23, 2014.
Mechanism of Action of undefined
Idelalisib binds to the protein called epidermal growth factor receptor (EFGR). As a result of this binding, cancer cells no longer receive the signal that the cells need for growth and development. Thus, this medication prevents cancer cells from growing.
Uses of undefined
Idelalisib is a targeted therapy medication that inhibits the delta isoform of PI3K (found in blood cells as B-cells and T-cells). By blocking PI3Kδ, Idelalisib disrupts signaling pathways that regulate cell survival, proliferation, and migration.
undefined Drug administaration and Dosage available
Take Idelalisib as advised by your physician. Usually, this medicine will be given twice a day. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking Idelalisib if your doctor advises you to stop.
Warnings, Precautions and Side Effects of undefined
Do not consume this medicine if you are allergic to Idelalisib, sunset yellow FCF (a petroleum-derived orange azo dye), and other ingredients of this medicine. Inform your physician if you have any conditions with the liver, lung (pneumonitis), kidney, intestinal perforation, neutropenia (low level of neutrophils), active infections/hepatitis, or skin reaction (Stevens-Johnson syndrome). Do not take this medicine if you are pregnant or think you might be pregnant or breastfeeding.
Before starting with Idelalisib, notify your doctor about all your underlying medical conditions. Your doctor may regularly monitor you to check the injection and functions of the respiratory system, kidney, lungs, liver, and other organs. Depending on the response to the treatment and other side effects, your doctor may adjust your dosage of the Idelalisin tablet. Notify your doctor if you are planning toget pregnant. Use effective contraception.
The most common side effects of Idelalisib are infections, liver damage, change in the number of WBC, increased liver enzymes, and lung inflammation.
Serious side effects while taking Idelalisib are reddish patches, changes in skin color, skin-peeling, mouth ulcers, ulcers in the throat, nose, genital, and eyes, skin rashes, fever, and dress syndrome (enlarged lymph nodes).
Word Of Advice
Keep out of sight and reach of pets and children. Store protected from light at a temperature not exceeding 30°C. Do not freeze. Oral contraception may be ineffective while under the treatment of Idelalisib. Discuss effective contraception methods with your doctor, along with fertility concerns. Do not stop the medicine until your doctor advises. Notify your doctor if you experience any serious side effects. Your doctor may change your dose or stop the treatment based on your response. This medicine is not recommended for children or adolescents.
Frequently Asked Question
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.