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Written By
Sakshi Anil More
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)

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Quick Summary
IMMUNOMODULATOR
Last updated on 31 Mar 2026 | 09:31 AM (IST)
IMMUNOMODULATOR
Background and Date of approval IMMUNOMODULATOR
Immunomodulators is an immunomodulator composed of heat-killed Mycobacterium W (Mw), indicated to treat NSCLC (Non-small Cell Lung Cancer) and other anticancer agents leading to improvement in overall response, quality of life, and survival of patients. It contains the active ingredient Mitomycin C, a type of chemotherapy drug. It can be used with other chemotherapy drugs or as a standalone treatment. Patients should avoid live vaccines while receiving Immunomodulators or several months after completing the treatment as the immune system may weaken. This medication can increase the risk of radiation-induced toxicity when combined with radiation therapy. Dose adjustments or close monitoring may be required in such patients.
Uses of IMMUNOMODULATOR
Immunomodulator is an immunomodulatory agent used as adjuvant therapy in treating various types of cancer, including gastric, colorectal, and breast cancer.
How is IMMUNOMODULATOR administered?
Immunomodulator is a medication administered intravenously (IV) by a healthcare professional. It is important to follow the healthcare provider's instructions regarding the dosage and administration of medication. Refrain from doubling the dose to make up for missed doses.
Side Effects of IMMUNOMODULATOR
Immunomodulator can cause several side effects, both common and serious. Common side effects may include pain, swelling, redness at the injection site, fever, headache, fatigue, nausea, vomiting, and diarrhea. Serious side effects may include anaphylactic shock, severe hypersensitivity reactions, and pulmonary embolism.
Warnings
It is important to be aware of the warnings associated with immunomodulators. This medication can cause severe hypersensitivity reactions or anaphylactic shock in patients who are allergic to it. It is also not recommended for use in patients with autoimmune disorders or those who are immunocompromised. Other warnings include the potential for cardiac events, liver and kidney damage, and pulmonary embolism.
Precautions
Patients with a history of severe hypersensitivity reactions or anaphylactic shock should not receive Immunomodulators. It is also not recommended for use in patients with autoimmune disorders or those who are immunocompromised. Patients with a history of cardiac events, liver or kidney disease, or pulmonary embolism should be closely monitored during Immunomodulators.
Word of Advice
If you are prescribed Immunomodulators or any other medication, it is important to carefully read and understand the warnings and precautions associated with the medication. Patients should be monitored for signs of an allergic reaction, such as rash, itching, or swelling, and should seek immediate medical attention if these symptoms occur. It should be used with caution in patients with severe renal impairment. Pregnant and breastfeeding women should discuss potential risk and benefit with a healthcare provider before taking this medication. Always maintain a healthy and balanced diet to support your overall health and well-being.
Frequently Asked Questions
Q1.
How Do Immunomodulators affect my kidney?
Immunomodulators can cause fluid retention and cardiovascular side effects such as chest pain, irregular heartbeats, and high blood pressure. Therefore, caution is advised in patients with pre-existing cardiovascular disease.
Q2.
What Precautions should I take if I have taken previous chemotherapy while taking Immunomodulators?
Patients who have previously received chemotherapy may have an increased risk of experiencing adverse effects or decreased drug efficacy when receiving Immunomodulators. Therefore, caution is advised in such patients.
Q3.
Can I take the vaccine while taking Immunomodulators?
It is generally safe to receive vaccines while taking Immunomodulators, but you should consult your healthcare provider to determine the best approach for your situation. It can affect the body's immune system and may impact certain vaccines' effectiveness.
Q4.
What is the difference between Immunomodulators and other cancer treatments?
Immunomodulators is an immunomodulatory therapy that stimulates the immune system to recognize and attack cancer cells. Other cancer treatments, such as chemotherapy and radiation therapy, kill cancer cells directly.
References
- Cadila Pharmaceuticals, [Revised on 2021] [Accessed on 12th Aug 2021], https://www.cadilapharma.com/research/worlds-first-innovation/
- Krunal Kavathiya., et al. “Desmocollin-3 and Cancer”. Acta Scientific Cancer Biology 3.9 (2019): 19-28, https://www.actascientific.com/ASCB/pdf/ASCB-03-0155.pdf
- Cancer Immunotherapy: Immune Suppression and Tumor Growth, Fourth edition, 2007, 507-536
Disclaimer
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.






