Isavuconazole was first approved by the U.S. FDA on March 6, 2015.

Isavuconazole is an azole antifungal medication used to treat Invasive Aspergillosis and Invasive Mucormycosis.

Isavuconazole is to be administered as prescribed by your healthcare provider. It is administered by two ways.

Isavuconazole capsule is administered either orally with or without food. Isavuconazole injection is administered as an infusion into the vein. 

Nausea, vomiting, diarrhea, headache, decreased appetite, low potassium level in blood, hallucinations, drowsiness, shortness of breath, sudden difficulty in breathing, inflamed veins causing blood clots, rash, itching, chest pain, fatigue, problem at the injection site are some common side effects of Isavuconazole. 

Hypersensitivity (rash, swelling on the lips, tongue, mouth), blisters around the mouth, eye, skin or genitals are some serious side effects that are commonly seen with the use of Isavuconazole.

Stop using Isavuconazole and inform your doctor immediately if you notice any signs of a severe allergic reaction like wheezing suddenly, trouble breathing, swelling of the face, lips, mouth or tongue, feeling severe itching, feeling dizzy or fainting, sweating, rapid heartbeat or pounding in the chest.

• Inform your doctor about any medications you are using before starting treatment with Isavuconazole.
• If you have any liver disease, inform your doctor before starting treatment with this medication. 
• Isavuconazole is not to be used in children and adolescents younger than 18 years.
• Isavuconazole may be harmful during pregnancy. Do not take this medication if you are pregnant or think that you might be pregnant unless prescribed to you by your doctor.
• Isavuconazole may be unsafe during breastfeeding. Do not breastfeed while taking this medication unless prescribed by your doctor.
• Isavuconazole is unsafe during driving and while operating machine as it can cause confusion, fatigue, and sleepiness. You might also pass out.

Do not use Isavuconazole unless prescribed by your doctor. You will have to do frequent blood tests to monitor your liver function. 

https://www.accessdata.fda.gov/drugsatfda_docs/nda/2015/207500Orig1207501Orig1s000TOC.cfm (Accessed on 27/07/2022)

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https://go.drugbank.com/drugs/DB11633 (Accessed on 27/07/2022)

https://pubchem.ncbi.nlm.nih.gov/compound/Isavuconazole#section=Related-Compounds(Accessed on 27/07/2022)

https://www.cresemba.com/frequently-asked-questions (Accessed on 27/07/2022)

https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/207500orig1s000lbl.pdf (revised date 03/2015) (Accessed on 27/07/2022)

https://www.medicines.org.uk/emc/files/pil.5069.pdf (Revised on 10/2021) (accessed on 27/07/2022)

https://www.drugs.com/cresemba.html (Accessed on 27/07/2022)

https://www.cresemba.com/dosing-administration (Accessed on 27/07/2022)

https://www.mrmed.in/medicines/cresemba-200mg-injection (Accessed on 27/07/2022)

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.