This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

L-arginine + proanthocyanidin granules combination is approved for medical use as dietary supplements in India.

Mechanism of Action of undefined

L-arginine + proanthocyanidin granules contain L-arginine and proanthocyanidin as active components. L-arginine is a non-essential amino acid that helps to relax blood vessels and improve blood flow. It also helps to produce nitric oxide, a vasodilator that helps improve blood pressure and circulation. Proanthocyanidin is a grape seed extract and an antioxidant that helps to strengthen blood vessels. It also has anti-inflammatory and anti-diabetic effects.

Uses of undefined

L-arginine + proanthocyanidin granules are a combination of vital nutrients, particularly for pregnant women, as they promote the growth and development of both the baby and the mother. These granules have diverse health benefits and are used to manage nutritional deficiencies, heart disease, high blood pressure, and enhanced blood sugar levels related to diabetes. They also aid in treating erectile dysfunction and enhancing athletic performance. Specifically designed to enhance blood supply to the placenta and fetus, these supplements are given to pregnant women at risk of conditions like pre-eclampsia (high blood pressure and high protein in urine during pregnancy) and intrauterine growth restriction (IUGR), which hampers normal fetal weight gain during pregnancy.

undefined Drug administaration and Dosage available

L-arginine + proanthocyanidin granules combination is available as a 6.5gm sachet for oral intake directed by a physician. Your doage and duration will be determined by your healthcare provider based on the severity of your condition.

Warnings, Precautions and Side Effects of undefined


Individuals with guanidinoacetate methyltransferase deficiency (GAMT) should avoid this supplement due to their inability to convert arginine and related compounds into creatine, which might lead to complications. Before using this medication, inform your doctor if you have a medical history of kidney or heart disease. Additionally, it is crucial to know that L-Arginine + Proanthocyanidins Sachets may interfere with blood pressure regulation during and after surgery. To avoid complications, it is advised to stop these supplements at least two weeks before any scheduled surgery is advised, following consultation with a healthcare professional.


It is  crucial to notify your doctor before using L-arginine + proanthocyanidin supplements during pregnancy. Limited information exists about their safety for breastfeeding mothers and individuals with liver or lung conditions. The compatibility with alcohol consumption is uncertain. If you experience dizziness, it's advisable to refrain from driving and consult your doctor promptly for guidance.

Side Effects

L-arginine + proanthocyanidin granules supplement is generally safe to consume and is not associated with significant side effects. However, consult your physician for more advice if you experience any unfamiliar side effects.

Word Of Advice

Before incorporating L-arginine + proanthocyanidin into your routine, it is crucial to consult your doctor, especially if you have existing health issues or are currently on medication. Begin with a low dosage and gradually increase it as your body tolerates. Ensure to stay within the prescribed daily limit. Stay vigilant about possible side effects, and if you encounter any adverse reactions, discontinue the supplement immediately. Your doctor's guidance ensures safe and effective usage tailored to your specific health needs. Your physician may advise regular kidney function tests and electrolyte monitoring, as L-arginine in L-arginine + proanthocyanidin may cause increased potassium levels when used by people with kidney disease.

To maintain optimal health, focus on a balanced diet comprising whole grains, vegetables, and fruits. Avoid harmful habits such as smoking and excessive alcohol consumption. Maintain a healthy body weight through nutritious eating and regular exercise. Incorporate calcium and magnesium-rich foods like prunes, raisins, and orange juice into your diet. Opt for low-fat dairy options like yogurt, milk, and cheese. Substitute unhealthy snacks with nutritious alternatives such as unsalted nuts and frozen yogurt. Additionally, be mindful of hidden fats in processed foods like chips and pastries, opting instead for cooking oils rich in omega-3 fatty acids. These lifestyle choices can significantly enhance your overall well-being.

Frequently Asked Question


  1. Biobricpharma, Manufacturer; [Accessed on 20th Oct 20223]
  2. Kiani AK, et al., Dietary supplements for improving nitric-oxide synthesis; J Prev Med Hyg, Published on Oct 2022; Accessed on 20/10/2023;
  3. Xie Y, et al., Proanthocyanidins: A novel approach to Henoch‑Schonlein purpura through balancing immunity and arresting oxidative stress via signaling pathway (Review); Exp Ther Med; Published on May 2023; Accessed on 20/10/2023;


The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.