This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
The U.S. FDA approved Latanoprost + Timolol for ocular use in 1996. Latanoprost belongs to the group of medicines called prostaglandin analogs which increases the natural outflow of fluid from the eye into the bloodstream. Timolol belongs to a group of medicines known as beta-blockers. It slows down the production of the fluid in the eye.
Mechanism of Action of undefined
Latanoprost + Timolol works by dual mechanism to lower intraocular pressure (IOP) in the eye. Latanoprost, a prostaglandin analog, enhances fluid drainage from the eye, reducing IOP. Timolol, a beta-blocker, reduces fluid production in the eye. Together, they effectively regulate IOP, aiding in the management of conditions like glaucoma.
Uses of undefined
Latanoprost + Timolol treats open-angle glaucoma and ocular hypertension in adults. They work by reducing the pressure in the eye and enhancing the natural drainage of fluid from the eye into the bloodstream.
undefined Drug administaration and Dosage available
Use the Latanoprost + Timolol as your physician advises. Do not take more or less of the eye drops than your doctor has instructed. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.
Warnings, Precautions and Side Effects of undefined
Do not use Latanoprost + Timolol if you are allergic to Latanoprost, Timolol, beta-blockers, or any other ingredients. Avoid using them if you have or had respiratory issues like asthma or severe chronic obstructive bronchitis. These drops are not suitable if you have significant heart problems or heart rhythm disorders. Latanoprost + Timolol should be used cautiously in lung patients. Before starting the treatment, inform your physician about pre-existing lung conditions. Do not use this eyedrop if you are pregnant, think you may be pregnant, plan to get pregnant, or are breastfeeding. Before using this eye drop, consult your doctor if you or your child have or have had conditions such as coronary heart disease, heart failure, low blood pressure, or slow heartbeat. These eye drops are suitable for adult men and women, including the elderly, but should not be used by individuals under the age of 18.
Notify your doctor if you have breathing problems like asthma or chronic obstructive pulmonary disease, poor blood circulation diseases like Raynaud's disease, diabetes, overactivity of the thyroid gland, or are about to undergo eye surgery. Report to your doctor if you have experienced eye problems like pain, irritation, inflammation, or blurred vision or if you know you have dry eyes, wear contact lenses, suffer from angina, severe allergic reactions, or have had a viral eye infection caused by the herpes simplex virus. Let your doctor know before any surgery, as these eye drops might interact with anesthesia medications.
The most common side effects of Latanoprost + Timolol are gradual change in eye color (increasing brown pigment), redness of the eye, eye irritation (burning, itching, stinging), changes to eyelashes and fine hairs around the treated eye (mainly in people of Japanese origin), irritation or disruption to the eye surface, eyelid inflammation (blepharitis), eye pain, and light sensitivity (photophobia).
Word Of Advice
It is essential to remove your contact lenses before using this eye drops. After applying the eye drops, wait for 15 minutes before putting the contact lenses back in to avoid any potential interactions. Moreover, if you need to use other eye drops in addition to Latanoprost + Timolol, make sure to wait at least five minutes before using them to ensure their effectiveness and minimize any possible adverse effects. Following these instructions can help you use the eye drops safely and effectively while maintaining good eye health. It is advised not to put too many drops in your eye, which can lead to slight irritation, watering, and redness. If you have any concerns, contact your doctor.
Frequently Asked Question
- Tubilux pharma S.p.A; Electronic medicines compendium (emc); [Revised on March 2022] [ Accessed on 26th July 2023] *pil.6945.pdf (medicines.org.uk)
- Pfizer; [Accessed on 26th July 2023], http://labeling.pfizer.com/ShowLabeling.aspx?id=613
- Pfizer; U.S Food & Drug Administration FDA; [Revised on June 2014] [ Accessed on 26th July 2023.] https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020597s045s048lbl.pdf
- Jeffrey D. Henderer and Christopher J. Rapuano, Ocular Pharmacology, Goodman & Gilman's Pharmacological Basis of Therapeutics, 2011, Page 1773-1801.
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.