This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Leuprolide Acetate is a gonadotropin-releasing hormone (GnRH) agonist approved for its medical use on 9th April 1985.
Mechanism of Action of undefined
Leuprolide Acetate Injection is a biological agent that acts as hormonal drug therapy in cancer treatment. It comes under the class of Gonadotropin-releasing hormone (GnRH) agonist. It stimulates the luteinizing hormone and follicle-stimulating hormone of the pituitary gland, resulting in high estrogen in females and high testosterone and dihydrotestosterone in males. With continuous use, the levels of these hormones fall, and the organs which depend on these hormones become inactive. It is often administered in combination with other medications to alleviate pain symptoms.
Uses of undefined
Leuprolide Acetate Injection has been developed to treat solid tumors by injecting it directly into the bloodstream. Leuprolide Acetate Injection has been approved to treat several conditions such as prostate cancer, endometriosis, uterine fibroids and other hormonal conditions.
undefined Drug administaration and Dosage available
Leuprolide acetate Injection is available in different doses. This injection will be mostly administered by your doctor or nurse on your arm, thigh or abdomen after preparation. The site of injecting this medicine will be changed regularly. Your healthcare provider will administer this medicine once in three months.
Warnings, Precautions and Side Effects of undefined
Contact your doctor immediately if you experience shortness of breath, severe rash, rapid heartbeat or blood in cough. During the treatment with Leuprolide Acetate injection treatment, your doctor may periodically monitor your blood cholesterol and liver parameters to prevent serious complications. Report to your doctor if you have had a history of diabetes, bone problems or heart failure. Get immediate medical attention if you have pain, weakness or loss of sensation in your legs or difficulty passing urine.
Leuprolide Acetate is not recommended for use during pregnancy and breastfeeding. It is essential to discuss possible contraceptive methods with your healthcare provider before beginning this treatment.
The common side effects that are likely to occur while you are on the treatment with Leuprolide Acetate Injection are hot flashes, headache, vaginal inflammation for women, depression, weight loss/gain, pain, nausea, vomiting, low libido and dizziness. If you experience any reactions such as excessive sweating, breathlessness, severe headache, report to your doctor immediately.
Word Of Advice
If you experience dizziness, tiredness or any visual disturbances, you should avoid driving or handling machines. Maintain adequate nutrition and fluid intake. Wear protective clothing and apply good quality sunscreen to protect your skin.
Frequently Asked Question
- AbbVie Inc., US Food & Drug Administration, [Revised on Feb 2021] [Accessed on 12th April 2023 ], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/020011s042,019943s035lbl.pdf
- Dallas V. Swayzer; Valerie Gerriets, StatPearls [Internet], [Revised on 11th Jul 2022] [Accessed on 12th April 2023], https://www.ncbi.nlm.nih.gov/books/NBK551662/
- Takeda UK Limited, Electronic Medicines Compendium (EMC), [Revised on Jun 2022] [Accessed on 13th Aug 2022], https://www.medicines.org.uk/emc/files/pil.4651.pdf
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.