This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Megaldrate + Simethicone + Oxetacaine belongs to the medication class known as anti-ulcers and antacids, which treat digestion-related problems. 

Mechanism of Action of undefined

Magaldrate functions by neutralizing excess stomach acid. Simethicone, also known as activated dimethicone, combines silica gel and dimethicone. It reduces the surface tension of gas bubbles, facilitating their release through belching or flatulence. It also prevents gas accumulation in the digestive system. Oxetacaine provides pain relief by numbing the stomach and alleviating discomfort caused by ulcers or acidic injuries.

Uses of undefined

Megaldrate + Simethicone + Oxetacaine treats acidity, indigestion, heartburn, and stomach upset. Magaldrate neutralizes excess stomach acid, Simethicone reduces gas bubble surface tension for easier elimination through belching or flatulence, while oxetacaine numbs and relieves stomach pain from ulcers or acidic injury.

undefined Drug administaration and Dosage available

Take the Megaldrate + Simethicone + Oxetacaine as your physician advises. Before use, carefully read the directions on the label. Use a measuring cup to ensure accurate dosage, and take it orally. Shake the bottle well before use. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Warnings, Precautions and Side Effects of undefined


Megaldrate + Simethicone + Oxetacaine should not be consumed if you are allergic to Megaldrate + Simethicone + Oxetacaine or any of its ingredients in the medication. Before taking Megaldrate + Simethicone + Oxetacaine, it is important to inform your doctor if you have a history of appendicitis, bowel blockage, rectal bleeding, kidney problems, are on a low-magnesium diet, or have recently undergone bowel surgery.  It is advisable to avoid taking antacids that contain aluminum and magnesium with Dimethicone and Megaldrate because that may result in constipation and intestinal obstruction, while magnesium-containing antacids could cause diarrhea. 


Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or breastfeeding. Notify your physician if you are taking other medicine to avoid interaction and side effects. Avoid exceeding the recommended duration of use for this medication.

Side Effects

The most common side effects of Megaldrate + Simethicone + Oxetacaine are a chalky taste, intestinal pain, diarrhea,  and constipation.

Word Of Advice

Inform the doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. It is important to consult your doctor before consuming Megaldrate + Simethicone + Oxetacaine if you are breastfeeding. Notify your doctor if you experience any side effects. Contact your doctor for more information. Avoid consuming alcohol. If you experience symptoms of appendicitis or inflamed bowel, such as lower abdominal pain, cramping, bloating, nausea, or vomiting, inform your doctor immediately.

Frequently Asked Question


  1. Hoogerwerf WA, Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 967-981.
  2. K.D. Tripathi,  Drugs for peptic ulcer, and G.E.R.D. Essentials of medical pharmacology. Seventh edition. 2013. Page – 655.
  3. Curtis J. Ingold, Hossein Akhondi. Simethicone. NIH National Library of Medicine, National Center for Biotechnology Information [Published on July 2022] [Accessed on 01st July 2023]
  4., [Accessed on 01st July 2023]
  5., [Accessed on 01st July 2023]


The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.