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Written By
Sakshi Anil More
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)

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MEGALDRATE,SIMETHICONE,OXETACAINE
Last updated on 31 Mar 2026 | 09:30 AM (IST)
MEGALDRATE,SIMETHICONE,OXETACAINE
Background and Date of approval MEGALDRATE,SIMETHICONE,OXETACAINE
Megaldrate + Simethicone + Oxetacaine belongs to the medication class known as anti-ulcers and antacids, which treat digestion-related problems.
Uses of MEGALDRATE,SIMETHICONE,OXETACAINE
Megaldrate + Simethicone + Oxetacaine treats acidity, indigestion, heartburn, and stomach upset. Magaldrate neutralizes excess stomach acid, Simethicone reduces gas bubble surface tension for easier elimination through belching or flatulence, while oxetacaine numbs and relieves stomach pain from ulcers or acidic injury.
How is MEGALDRATE,SIMETHICONE,OXETACAINE administered?
Take the Megaldrate + Simethicone + Oxetacaine as your physician advises. Before use, carefully read the directions on the label. Use a measuring cup to ensure accurate dosage, and take it orally. Shake the bottle well before use. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Side Effects of MEGALDRATE,SIMETHICONE,OXETACAINE
The most common side effects of Megaldrate + Simethicone + Oxetacaine are a chalky taste, intestinal pain, diarrhea, and constipation.
Warnings
Megaldrate + Simethicone + Oxetacaine should not be consumed if you are allergic to Megaldrate + Simethicone + Oxetacaine or any of its ingredients in the medication. Before taking Megaldrate + Simethicone + Oxetacaine, it is important to inform your doctor if you have a history of appendicitis, bowel blockage, rectal bleeding, kidney problems, are on a low-magnesium diet, or have recently undergone bowel surgery. It is advisable to avoid taking antacids that contain aluminum and magnesium with Dimethicone and Megaldrate because that may result in constipation and intestinal obstruction, while magnesium-containing antacids could cause diarrhea.
Precautions
Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or breastfeeding. Notify your physician if you are taking other medicine to avoid interaction and side effects. Avoid exceeding the recommended duration of use for this medication.
Word of Advice
Inform the doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. It is important to consult your doctor before consuming Megaldrate + Simethicone + Oxetacaine if you are breastfeeding. Notify your doctor if you experience any side effects. Contact your doctor for more information. Avoid consuming alcohol. If you experience symptoms of appendicitis or inflamed bowel, such as lower abdominal pain, cramping, bloating, nausea, or vomiting, inform your doctor immediately.
Frequently Asked Questions
Q1.
How to manage the side effects of Megaldrate + Simethicone + Oxetacaine?
To manage the side effects of Megaldrate + Simethicone + Oxetacaine, follow the prescribed dosage, and report side effects promptly. Drink plenty of water throughout the day to stay hydrated. If you experience a chalky taste, you can try rinsing your mouth with water or chewing sugar-free gum to alleviate the sensation. This can help prevent or reduce symptoms. Maintain a healthy lifestyle, and attend follow-up appointments.
Q2.
Can you take Megaldrate + Simethicone + Oxetacaine when pregnant?
Consult your medical professional regarding the usage of Megaldrate + Simethicone + Oxetacaine during pregnancy. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it's necessary.
Q3.
What should I do if I miss a dose of Megaldrate + Simethicone + Oxetacaine?
If you miss a dose, take it as soon as possible. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose the Megaldrate + Simethicone + Oxetacaine.
Q4.
What are the common side effects of Megaldrate + Simethicone + Oxetacaine?
The common side effects of Megaldrate + Simethicone + Oxetacaine are a chalky taste, intestinal pain, diarrhea, constipation, and allergic reaction.
Q5.
What are the ingredients present in Megaldrate + Simethicone + Oxetacaine?
Megaldrate + Simethicone + Oxetacaine contains three active ingredients known as Megaldrate, Simethicone, and Oxetacaine. If you experience any symptoms, contact your doctor immediately.
Q6.
How to store Megaldrate + Simethicone + Oxetacaine?
Store the Megaldrate + Simethicone + Oxetacaine at a temperature of 30ºC. Always keep out of sight and reach of pets and children. Do not freeze the medicine.
References
- Hoogerwerf WA, Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 967-981.
- K.D. Tripathi, Drugs for peptic ulcer, and G.E.R.D. Essentials of medical pharmacology. Seventh edition. 2013. Page – 655.
- Curtis J. Ingold, Hossein Akhondi. Simethicone. NIH National Library of Medicine, National Center for Biotechnology Information [Published on July 2022] [Accessed on 01st July 2023] https://www.ncbi.nlm.nih.gov/books/NBK555997/
- Drug.com, [Accessed on 01st July 2023] https://www.drugs.com/cdi/magaldrate-and-simethicone.html
- Drug.com, [Accessed on 01st July 2023] https://go.drugbank.com/drugs/DB12532
Disclaimer
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.






