This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Methylergometrine was initially approved by the United States Food and Drug Administration (FDA) on June 29, 1948.

Mechanism of Action of undefined

Methylergometrine works by stimulating the smooth muscle cells in the uterus to contract, which helps the uterus to constrict and reduce blood flow. This can be particularly beneficial in preventing or treating postpartum hemorrhage.

Uses of undefined

Methylergometrine is utilized to prevent or treat excessive bleeding following childbirth or abortion. Belonging to the ergot alkaloid class of drugs, it induces uterine contractions, aiding in the reduction of postpartum hemorrhage by promoting the closure of blood vessels within the uterus.

undefined Drug administaration and Dosage available

Methylergometrine is usually administered as an intramuscular injection, though it can also be given orally or intravenously, depending on the situation and the healthcare provider's judgment.

Warnings, Precautions and Side Effects of undefined


Methylergometrine can cause a sudden and severe increase in blood pressure, leading to hypertensive crisis. The medication's vasoconstrictive properties can impact the cardiovascular system, potentially causing chest pain, irregular heartbeats, and other heart-related issues. It can trigger seizures, especially in individuals with a history of seizure disorders. Due to its potential to affect blood pressure and blood vessels, may increase the risk of stroke, especially in individuals with preexisting risk factors.


Individuals with hypertension or high blood pressure should use Methylergometrine cautiously due to its potential to increase blood pressure further. People with heart conditions, angina, or a history of heart problems should use this medication cautiously due to its impact on cardiovascular function. Its use may require caution or dose adjustment in individuals with severe liver or kidney impairment.

Side Effects

Common side effects of Methylergometrine include nausea, vomiting, headache, uterine cramps, and increased blood pressure. More serious side effects may include chest pain, seizures, severe headaches, and hypertensive crisis (dangerously high blood pressure). 

Word Of Advice

People with high blood pressure, heart issues, or past heart problems should be cautious because Methylergometrine can raise blood pressure and affect the heart. If you have liver or kidney problems, use the medicine carefully. People with blood vessel issues or migraines should also be cautious. Talk to your doctor if you're pregnant or breastfeeding, especially with conditions like preeclampsia or placental issues. The medicine can interact with other drugs, alcohol, and grapefruit juice, so be careful. It might make you feel dizzy, affecting activities like driving. Tell your doctor about your medical history, including seizures or allergies. Although the medicine can help with bleeding after childbirth, it might not be right for other urgent situations. Watch out for serious side effects like bad headaches or chest pain. Always follow your doctor's instructions and ask them if you're unsure.

Frequently Asked Question


  1. Novartis Pharmaceuticals Corporation, US Food & Drug Administration, [Revised on June 2012] [Accessed on 31st Aug 2023],/
  2. hameln pharma ltd, Electronic medicines compendium (EMC), [ Revised on31st Aug 2023] [Accessed on August 31st, 2023],


The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.