This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Octreotide has been approved to treat acromegaly by the U.S. FDA approved on June 26, 2020.

Mechanism of Action of undefined

Somatostatin is a hormone produced by the body on its own. It reduces or stops the production of several hormones, including insulin and gut hormones, and it also regulates the stomach and intestinal emptying.

Octreotide is a somatostatin analog that is made synthetically and slows down hormone production. It helps ease carcinoid syndrome, a type of cancer called carcinoid tumors that release certain chemicals into your bloodstream and slows the spread of the tumor. Flushing of the skin, diarrhea, and stomach pain are a few of the symptoms of carcinoid syndrome you could experience.

Uses of undefined

Octreotide treats acromegaly, carcinoid tumors, and vasoactive intestinal peptide tumors (VIPoma).

undefined Drug administaration and Dosage available

Octreotide is available as an immediate-release solution (liquid) for injection in the doses of 10 mg, 20 mg, and 30 mg. It is intended for administration via the subcutaneous or intravenous route. It must be administered only under the supervision of a healthcare professional at around the same time every day. Check for discoloration and the presence of particles before injecting.

Warnings, Precautions and Side Effects of undefined

Warnings

Contact your physician immediately if you experience allergies to Octreotide and its ingredients. During the Octreotide injection treatment, your doctor may periodically monitor your blood sugar level, thyroid function, and liver or pancreatic enzyme function to prevent serious complications. Report to your doctor if you have an irregular heartbeat, gallstones, problems with blood sugar levels, either too high (hyperglycemia) or too low (hypoglycemia), or issues with the liver or kidneys. Discuss with your doctor if you have a medical history of vitamin B12 deficiency.

Precautions

If you are pregnant or planning to have a baby, consult a doctor before taking this medicine. Your healthcare provider will prescribe Octreotide only if it is necessary for you. Avoid breastfeeding your baby while on the treatment as it is unknown if Octreotide passes into the breastmilk.

Side Effects

The side effects known to occur commonly during the treatment with Octreotide are nausea, vomiting, bloating, diarrhea, abdominal pain, constipation, flatulence, hair loss, etc. This medicine could also alter your blood glucose, thyroid, and liver enzyme levels. Report to your doctor immediately if you experience difficulty breathing, rapid heartbeat, gall bladder abnormalities, blood glucose fluctuations, or hypothyroidism.

Word Of Advice

It is advised to let the Octreotide get to room temperature before using the medication if it is kept in the refrigerator. It reduces the possibility of pain at the injection site. It would be best if you didn't heat it, but you can warm it up in your palm. If you experience pain at the subcutaneous injection site, you can get relief by immediately rubbing the injection site lightly.

Frequently Asked Question

References

  1. Hospira U.K.  Limited, Electronic Medicines Compendium (EMC), [Revised on May 2022] [Accessed on 16th Aug 2022], https://www.medicines.org.uk/emc/files/pil.375.pdf
  2. Novartis pharmaceuticals corporation, U.S. Food and Drug Administration, [Revised on 2002] [Accessed on 16th Aug 2022],

Disclaimer

The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.