Uses of undefined

Paclitaxel, Human Albumin, is FDA-approved for the treatment of:

• Metastatic breast cancer.
• Non-small cell lung cancer (in combination with carboplatin).
• Metastatic pancreatic cancer (in combination with gemcitabine).

undefined Drug administaration and Dosage available

This medication is administered as an intravenous infusion under medical supervision. The dosage varies depending on the type and severity of the cancer and the patient’s overall condition. Commonly available dosages include:

• 100 mg/vial
• 250 mg/vial

Treatment is typically repeated every three weeks, with adjustments made based on the patient’s response and tolerance.

Warnings, Precautions and Side Effects of undefined

Warnings

• Severe hypersensitivity reactions: Avoid in patients with prior severe allergic reactions to paclitaxel or albumin.
• Myelosuppression: Can lead to dangerously low white blood cell counts and infections.
• Peripheral neuropathy: High risk of nerve damage, requiring monitoring for symptoms.
• Liver impairment: Requires dosage adjustments in patients with hepatic dysfunction.
• Pregnancy and lactation: Not recommended due to potential harm to the fetus or nursing infant.

Precautions

Patients should inform their healthcare provider about existing medical conditions, especially liver disease, low blood counts, or neuropathy. Regular blood tests are essential to monitor the impact of treatment. It is crucial to avoid grapefruit or grapefruit juice as they may interfere with drug metabolism. Women of childbearing age should use effective contraception during and after treatment to prevent pregnancy-related risks. Maintaining hydration and reporting any unusual symptoms, such as fever or unusual bleeding, are critical during therapy.

Side Effects

Common Side Effects

• Fatigue and weakness
• Hair loss (alopecia)
• Nausea and vomiting
• Joint and muscle pain
• Diarrhea

Serious Side Effects

• Severe neutropenia (low white blood cell count)
• Peripheral neuropathy (tingling or numbness in extremities)
• Allergic reactions (rash, difficulty breathing)
• Pulmonary toxicity
• Cardiovascular complications such as low blood pressure

Word Of Advice

This medication should be administered only in a clinical setting by trained professionals. Patients should adhere to the treatment schedule and report any persistent or severe side effects, such as unusual bruising or signs of infection. Eating a balanced diet and staying well-hydrated can help manage some side effects. Avoid any over-the-counter medications, herbal supplements, or significant dietary changes without consulting your doctor, as these may interact with the treatment.

Frequently Asked Question

• What is Paclitaxel, Human Albumin used for?
• This medication is primarily used to treat metastatic breast cancer, non-small cell lung cancer, and metastatic pancreatic cancer. It works by targeting rapidly dividing cancer cells and inhibiting their growth. The formulation combines paclitaxel with human albumin to improve drug delivery and reduce side effects. It offers an alternative for patients who cannot tolerate traditional solvent-based paclitaxel.

• How is Paclitaxel, Human Albumin administered?
• The drug is administered as an intravenous infusion under the supervision of a healthcare provider. The frequency of administration depends on the type of cancer being treated, but it is often given every three weeks. The infusion typically takes about 30 minutes to an hour. Dosage adjustments may be necessary based on the patient’s overall health and response to the treatment.

• What are the common side effects of this treatment?
• Common side effects include fatigue, nausea, hair loss, and joint or muscle pain. Patients may also experience mild diarrhoea or skin reactions. These side effects are generally manageable and temporary. It is important to notify your healthcare provider if side effects become severe or persistent.

• Can Paclitaxel, Human Albumin affect fertility?
• Yes, this medication may have an impact on fertility in both men and women. Women of childbearing age are advised to use effective contraception during and after the treatment period. Men should also discuss fertility preservation options with their doctor before starting therapy. Fertility typically recovers after treatment, but this depends on the individual case.

• Should I avoid certain foods or medications during treatment?
• Avoid grapefruit and grapefruit juice during treatment as they can interfere with the drug’s metabolism. Inform your doctor about all medications and supplements you are taking, as some may interact with the therapy. Maintaining a balanced diet can help manage side effects and support overall health during treatment. Always consult your healthcare provider before making any dietary or medication changes.