This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

 Palmitoylethanolamide + diacerein + biochanin A is a combination medication and was approved for medical use which helps in delaying the progression of chronic kidney disease (CKD) and relieves pain in diabetic peripheral neuropathy.

Mechanism of Action of undefined

The combination medication lessens inflammation, which may help ease pain and discomfort brought on by a number of illnesses. reduces pain and enhances joint function by delaying the deterioration of cartilage in osteoarthritis It also has anti-inflammatory properties and oxidative stress protecting actions that improve general health and overall well-being. It interacts with the endocannabinoid system and other pathways to reduce inflammation and modulate pain signals. This drug helps to alleviate the neuropathic pain associated with diabetes and relieves pain.

Uses of undefined

It is used in the treatment of chronic kidney disease by delaying its progression and relieves the pain in diabetic peripheral neuropathy. 

undefined Drug administaration and Dosage available

Palmitoylethanolamide + diacerein + biochanin A combination is available in oral dosage capsule form containing Palmitoylethanolamide 300 mg, diacerein 12.5 mg, Biochanin A 2.5 mg Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. It should be consumed as a whole not to chew,crush or bite. 

Warnings, Precautions and Side Effects of undefined


It is contraindicated in individuals with known hypersensitivity or allergy to this drug substance and the components in it. It is  recommended to inform your doctor if you face any reactions. 


Before starting the therapy, inform your doctor about any kidney or liver-related problems Pregnant and breastfeeding women should consult healthcare professionals before using this supplement, as safety during pregnancy and lactation has not been established.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Palmitoylethanolamide + diacerein + biochanin A is generally safe to consume and is not associated with significant side effects. However, consult your physician for more advice if you experience any unfamiliar side effects.

Word Of Advice

Tell your doctor immediately about all the medications you have been taking recently, including herbal and supplements, before taking this medicine. If you forget to take this medicine for the entire day, take your usual dose the next day. However, do not double-dose yourself. Throw away medicines that are no longer needed or are out-of-date. Keep medicines away from children and pets. Do not store these medicines in a damp place such as a bathroom, cabinet, or near the kitchen sink.

Frequently Asked Question


  1. Dibnepan, Biokindle [Accessed on 9th August 2023]
  2. Gabrielsson, L., Mattsson, S. and Fowler, C.J. (2016) Palmitoylethanolamide for the treatment of pain, Pharmacokinetics, safety and efficacy, British Journal of clinical pharmacology. [Accessed on 9th August 2023],
  3. Lang-Illievich, K. et al. (2023) Palmitoylethanolamide in the treatment of chronic pain: A systematic review and meta-analysis of double-blind randomized controlled trials, MDPI. [Accessed on 9th August 2023],


The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.