This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Pantoprazole sodium + Itopride hydrochloride belongs to the medication class proton pump inhibitors (PPIs) and prokinetic. It works by blocking the gastric proton pump enzyme. 

Mechanism of Action of undefined

Pantoprazole sodium + Itopride hydrochloride blocks the gastric proton pump enzyme to reduce acid production and accelerate gastric emptying, improving sensitivity and tension. This combination helps prevent acid reflux and provides relief from acidity.

Uses of undefined

Pantoprazole sodium + Itopride hydrochloride is used to treat gastroesophageal reflux disease. Additionally, it is also used to treat nocturnal acid breakthrough, diabetic gastroparesis, functional dyspepsia, and gastritis. Gastroesophageal reflux disease (GERD) is the backflow of stomach acid into the esophagus, causing discomfort. 

undefined Drug administaration and Dosage available

Take the Pantoprazole sodium + Itopride hydrochloride as your physician advises. Usually, the capsule will be taken with or without food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the capsule if your doctor advises you to stop.

Warnings, Precautions and Side Effects of undefined

Warnings

Do not consume Pantoprazole sodium + Itopride hydrochloride if you are allergic to Pantoprazole sodium, Itopride hydrochloride, or any of its ingredients in the medication. Before starting the treatment, inform your doctor if you have any history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. Long-term medication use may lead to osteoporosis and hypomagnesemia (low magnesium levels). Before taking Pantoprazole, notify your doctor if you have severe liver problems, a history of liver issues, reduced vitamin B12 levels, are taking HIV protease inhibitors, have osteoporosis, or have risk factors for fractures.

Precautions

Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or breastfeeding. Regular monitoring of liver enzymes and magnesium levels may be necessary. It is crucial to discuss your medical history and any concerns you may have with your healthcare provider to ensure the safe and appropriate use of the medication. It is unknown whether consuming alcohol while taking Pantoprazole sodium + Itopride hydrochloride is safe. Please speak with your physician.

Side Effects

The most common side effects of Pantoprazole sodium + Itopride hydrochloride are vomiting, bloating, postprandial fullness (an unpleasant sensation in the stomach), epigastric pain, and regurgitation.

Word Of Advice

Before starting the treatment, inform your doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose Pantoprazole sodium + Itopride hydrochloride  to make up for a forgotten dose. Notify your doctor if you experience any serious side effects. Contact your doctor for more information. 

Frequently Asked Question

References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Pharmacotherapy of acidity, ulcers, and reflux disease, 12th edition, 2011, 1311 - 1312.
  2. KD Tripathi, Essentials of Medical Pharmacology, Drugs for peptic ulcer and GERD, 7th edition, 2013, 653.
  3. Sun Pharmaceutical Industries Europe B.V, Electronic medicines compendium (EMC), [Revised on June 2020] [ Accessed on 4th July 2023], https://www.medicines.org.uk/emc/files/pil.2833.pdf
  4. Wyeth Pharmaceuticals Inc, US Food and Drug Administration, [Revised on Sept 2012] [ Accessed on 4th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020988s044lbl.pdf
  5. La Renon healthcare Pvt.Ltd, [ Accessed on 4th July 2023], https://www.larenon.com/wp-content/uploads/2018/10/Eiref.pdf

Disclaimer

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.