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Written By
Sakshi Anil More
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)
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Quick Summary
PEGYLATED INTERFERON BETA-1A
Last updated on 31 Mar 2026 | 09:31 AM (IST)
PEGYLATED INTERFERON BETA-1A
Background and Date of approval PEGYLATED INTERFERON BETA-1A
Pegylated Interferon Beta-1A is an immunomodulatory agent which was approved for its medical use on 18th August 2014.
Uses of PEGYLATED INTERFERON BETA-1A
Pegylated Interferon Beta-1A Injection has been developed to treat adults with relapsing forms of multiple sclerosis like clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease.
How is PEGYLATED INTERFERON BETA-1A administered?
Pegylated Interferon Beta-1A is available as a prefilled pen device for injection, intended for subcutaneous administration. It is available in the doses 63/94mcg and 125mcg. The usual dosing schedule is 63mcg on the first day, 94mcg on day 15 and 125mcg on day 29.
Side Effects of PEGYLATED INTERFERON BETA-1A
The common side effects that are likely to occur while you are on the treatment with Pegylated Interferon Beta-1A Injection are injection site reactions, chills, fever, headache, muscle pain, asthenia, pruritus, injection site pain, etc. If you experience any allergic reactions or discomfort after taking this injection, report to your doctor immediately.
Warnings
Contact your doctor immediately if you experience dizziness, fever, or infection. During the Pegylated Interferon Beta-1A injection treatment, your doctor may periodically monitor your blood pressure, blood sugar, electrolytes, heart, liver and kidney parameters to prevent serious complications. Report to your doctor if you have been diagnosed with other autoimmune disorders, depression, seizures, thyroid disorders or problems in your heart, liver or kidneys. Patients with severe liver and kidney impairment should exercise caution while using this medicine. Do not use this injection if you are allergic to interferon beta, rubber or latex.
Precautions
Pegylated Interferon Beta-1A is probably unsafe for use during pregnancy. Tell your physician before starting this treatment if you are pregnant, think you might be pregnant or planning to have a baby. It is not known if Pegylated Interferon Beta-1A passes into the breastmilk. However, it is advisable to tell your physician before starting this treatment if you are a breastfeeding mother or planning to breastfeed your child.
Word of Advice
Eat a well-balanced diet. If you feel dizzy or tired, you should avoid driving or handling machines. Do not touch or rub your skin after injecting this medicine. Wear loose-fitting clothes to avoid discomfort.
Frequently Asked Questions
Q1.
Can you inject Pegylated Interferon Beta-1A on your own?
You can inject Pegylated Interferon Beta-1A Injection on your own after receiving proper training from your healthcare provider.
Q2.
How to store Pegylated Interferon Beta-1A Injection?
Store Pegylated Interferon Beta-1A Injection in a refrigerator without freezing. Protect from light.
Q3.
What is the difference between interferon 1A and 1B?
The main difference between interferon 1A and 1B is that interferon-1A is more similar to the interferon naturally present in the human body.
Q4.
How long does it take for Pegylated Interferon Beta-1A to work?
It typically takes 1 to 2 hours of administration to experience effects and these effects last for a day.
Q5.
How is Pegylated Interferon Beta-1A Injection administered?
Pegylated Interferon Beta-1A is available as a prefilled pen device for injection, intended for subcutaneous administration. It is available in the doses 63/94mcg and 125mcg. The usual dosing schedule is 63mcg on first day, 94mcg on day 15 and 125mcg on day 29.
Q6.
How do you manage side effects of Pegylated Interferon Beta 1A Injection?
You can manage flu-like symptoms associated with the use of Pegylated Interferon Beta 1A by drinking sufficient water and taking over-the counter painkillers and fever medications.
Q7.
What can you expect from the MrMed patient assistance program?
MrMed’s Patient Assistance Program enables the patients to purchase medications at minimum cost. You can check your eligibility and the latest updates on PAP from the official website.
References
1. Biogen Inc., US Food & Drug Administration, [Revised on Mar 2022] [Accessed on 30th Sep 2022], https://www.plegridy.com/content/dam/commercial/plegridy/pat/en_us/pdf/plegridy-prescribing-information.pdf
2. Claus Madsen, The innovative development in interferon beta treatments of relapsing-remitting multiple sclerosis, Brain and Behavior, 2017, 7:e00696, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474703/pdf/BRB3-7-e00696.pdf
Disclaimer
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.
