Uses of undefined

Plerixafor is used to collect blood stem cells for collection, storage, and transplantation., lymphoma and multiple myeloma in adults, lymphoma or solid tumors in children (aged between 1 to 18). 

undefined Drug administaration and Dosage available

Plerixafor injection is administered as a subcutaneous injection (under your skin). If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.

Warnings, Precautions and Side Effects of undefined

Warnings

Before starting the treatment, notify your doctor if you have high WBC counts, low platelet counts, or a history of usual lightheaded or fainting, especially before injection. It is not advised to take this medicine for stem cell mobilization if you have leukemia. Do not take this medicine if you are allergic to Plerixafor or any other ingredients of this medicine. Report to your doctor if you have kidney disorders.

Precautions

Before starting the treatment, your doctor may monitor your liver function. your doctor may adjust the dose of the medicine if you have existing kidney disease. Your doctor may also perform a regular blood test to monitor the blood cell count. Do not take this medicine if you are pregnant or think you might be pregnant or if you breastfeeding. It is recommended to use effective contraception.

Side Effects

The most common side effects of Plerixafor are diarrhea, redness or irritation in the injection site, low RBC count (anemia), constipation, indigestion, dry mouth, numbness, joint pains, sweating, difficulty sleeping, and headache.

Serious side effects while taking Plerixafor are rashes, swelling around the eyes, difficulty in breathing, faintness, upper left abdomen pain, and left shoulder pain.

Word Of Advice

Report to your doctor if you experience any side effects like rashes or swelling around your eyes, a change in breathing (lack of oxygen), or pain in the upper left abdomen or left shoulder. Keep Plerixafor injection out of sight and reach of children. This medicine does not require any special storage conditions. Do not double the dose if missed the turn. Contact your doctor immediately if you double dose and for more concerns. 

Frequently Asked Question

• How can I manage the side effects associated with Plerixafor use? 
• Managing side effects of Plerixafor can include taking anti-nausea medication, staying hydrated, and resting. If you experience any severe or persistent side effects, it is important to speak with a healthcare provider. Hence, visit your doctor immediately. 

• Who should not take Plerixafor? 
• Plerixafor is not recommended for patients who have had an allergic reaction to Plerixafor or any of its ingredients. It is also not recommended for patients with certain medical conditions, such as severe kidney problems or low white blood cell counts. 

• How effective is Plerixafor in mobilizing stem cells? 
• Studies have shown that Plerixafor in combination with G-CSF is highly effective in mobilizing stem cells from the bone marrow into the bloodstream. 

• What if I missed my dose of Plerixafor? 
• If you missed your regular injection, contact your doctor as soon as possible.  

• How is Plerixafor administered? 
• Plerixafor Injection is given as a subcutaneous injection, which means it is injected under the skin, typically in the stomach or thigh. 

• Why I should not consume alcohol while taking Plerixafor?  
• Plerixafor is metabolized by the liver, and alcohol can also affect liver function. Therefore, consuming alcohol while taking Plerixafor can potentially impact its effectiveness and increase the risk of liver damage. Also, alcohol can increase the risk of certain side effects associated with Plerixafor, such as dizziness, drowsiness, and lightheadedness.