This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Rabeprazole + levosulpiride is approved medical product used to treat gastroesophageal reflux disease and irritable bowel syndrome.

Mechanism of Action of undefined

The medication inhibits the function of a particular protein known as interleukin 6, which plays a role in the body's inflammatory responses. By blocking this protein, it can help decrease inflammation within your body.

Uses of undefined

It is used to treat gastroesophageal reflux disease (GERD). It is also indicated to treat intestinal ulcers and irritable bowel syndrome (IBS).

undefined Drug administaration and Dosage available

Rabeprazole + Levosulpiride works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and ulcers. Rabeprazole works by inhibiting acid production in the stomach by working on a pump in the stomach called the proton pump, which is responsible for acid secretion. Levosulpiride acts by boosting stomach and intestine motility, preventing acid from refluxing back into the food pipe.

Warnings, Precautions and Side Effects of undefined


Do not take Rabeprazole + Levosulpiride if you are allergic to rabeprazole, levosulpiride, or any of the other ingredients. This medicine is not recommended for use in children. This medicine can cause a decrease in the WBC and platelet counts. So, your doctor will monitor your blood tests regularly. 


Inform your physician if you have liver problems, heart diseases, kidney disorders, bone diseases, mental disorders, and any other diseases before initiating the treatment. Before starting the treatment, inform your physician if you are pregnant, breastfeeding, or planning to get pregnant. The most common side effects of Rabeprazole + Levosulpiride are nausea, stomach pain, diarrhea, flatulence, constipation, headache, weakness, and flu-like symptoms. Do not stop taking this medicine without consulting a doctor. Take this medicine as long as your doctor recommends you take it. 

Side Effects

The common side effects that are experienced while you are on the treatment with Rabeprazole + levosulpiride cough, sore throat, nausea, vomiting, back pain, abdominal pain, diarrhea, constipation, sleeplessness, headache, dizziness, infection, flu like symptoms. Report your doctor immediately, if you experience severe allergic reactions, yellow skin, dark urine, skin blisters or peeling. 

Word Of Advice

Do not take a double dose to make up for a forgotten dose. If you forget to take a dose, take it as soon as you remember. If it is almost time to take the next dose, wait until then. Inform your physician immediately if you face excessive drowsiness, yellowing of the skin, and dark urine because this may indicate liver problems. This medicine should be used with caution in patients who are suffering from diabetes or are exposed to the risk factors. Avoid or limit alcohol while taking this medicine.  Your doctor may take routine blood tests to check for the effectiveness of the therapy. 

Frequently Asked Question


  1. Cipla Ltd., Prescribing information, [Revised on January 2020] [Accessed date June 16th 2023]
  2. Mansi C, Savarino V, Vigneri S, Perilli D, Melga P, Sciabà L, De Martini D, Mela GS. Gastrokinetic effects of levosulpiride in dyspeptic patients with diabetic gastroparesis. Am J Gastroenterol. 1995 Nov;90(11):1989-93.
  3. Lozano R, Concha MP, Montealegre A, de Leon L, Villalba JO, Esteban HL, Cromeyer M, García JR, Brossa A, Lluberes G, Sandí EI, Quirós HB. Effectiveness and safety of levosulpiride in the treatment of dysmotility-like functional dyspepsia. Ther Clin Risk Manag. 2007 Mar;3(1):149-55.


The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.