This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Recombinant human epidermal growth factor was approved for medical use to enhance wound healing in burns and diabetic foot ulcers.

Mechanism of Action of undefined

Recombinant human epidermal growth factor (rhEGF) gel promotes wound healing by stimulating cell growth and differentiation. An epidermal growth factor is a small mitogenic protein associated with mechanisms such as normal cell growth and wound healing, reducing the healing time.

Uses of undefined

Recombinant human epidermal growth factor is used for the faster healing of diabetic foot ulcers in patients with diabetes and helps to prevent the amputation (a process of surgical removal of all or part of body extremity) in such patients. The lower strength of this medicine is used for first and second-degree burns, skin grafts and also in the management of bedsores.

undefined Drug administaration and Dosage available

Recombinant human epidermal growth factor is available as a gel with three different strengths: 7.5g, 15g, and 30g  for topical use. To be used only when directed by a physician.

Warnings, Precautions and Side Effects of undefined


Before using recombinant human epidermal growth factor (rhEGF) gel, it is crucial to inform your physician if you are pregnant, breastfeeding, have lung or liver conditions, or are uncertain about potential interactions with alcohol. Exercise caution and seek medical advice to ensure the gel's safety in these situations.


To ensure the safe application of recombinant human epidermal growth factor gel, keep it out of reach of children, and perform a patch test before widespread use. Apply the gel topically using a sterile cotton swab as directed by the physician, avoiding direct contact with the wound. Clean the wound area before each application, use a single tube per patient, and adhere to the specified instructions. Consult your healthcare provider for personalized guidance based on your medical history.

Side Effects

Side effects are undesirable symptoms that can result from medication use, although not everyone may experience them. Common side effects associated with using this gel include redness of the skin, skin rash, skin discoloration, skin irritation, a burning sensation on the skin, and dry skin. It's essential to be aware of these potential effects and consult with your healthcare provider if you encounter any persistent or bothersome symptoms during the course of using the gel.

Word Of Advice

For optimal results with recombinant human epidermal growth factor gel, adhere to precise application guidelines. Use a single tube exclusively, avoid over-the-counter usage, and ensure the gel is within its shelf life. Keep the application external, steering clear of eye contact. Pre-cleanse the affected area, and maintain open communication with your healthcare provider, discussing your medical history and medications. This collaborative approach enhances the gel's efficacy and fosters an effective healing journey.

Frequently Asked Question


  1. Bharath Biotech International, Manufacturer, [Accessed on Nov 2023]
  2. Hong JP, et al., Recombinant human epidermal growth factor (EGF) to enhance healing for diabetic foot ulcers. Ann Plast Surg [Published in Apr 2006] [Accessed in Nov 2023]


The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.