This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Ribavirin is an antiviral medicine containing the active constituent ribavirin. It treats chronic hepatitis C in patients aged three years and older. Hepatitis C (a liver infection) occurs due to the hepatitis C virus (HCV). It is always given with other medicines to treat hepatitis C infection. This antiviral medication should not be used if a person has a history of heart attack or severe heart disease in the past six months, has blood disorders (abnormal red blood cells and hemoglobin) or severe kidney problems, or takes didanosine (which treats HIV infection). Ribavirin received FDA approval for its use in various indications on June 6, 1985.
Mechanism of Action of undefined
Ribavirin is therapeutic in treating chronic hepatitis C virus (HCV) infection. It works by inhibiting viral replication, thereby reducing the viral load in the body and improving liver function. The combination therapy helps achieve sustained virologic response (SVR), which indicates a successful treatment outcome with long-term virus clearance.
Uses of undefined
Ribavirin is used in the treatment of chronic hepatitis C infection.
undefined Drug administaration and Dosage available
Ribavirin Tablet is taken orally. The medication is taken once a day, either with or can be taken without food, as directed by your healthcare provider. Swallow the capsule or tablet whole without crushing or chewing it.
Warnings, Precautions and Side Effects of undefined
Ribavirin warnings include its contraindication during pregnancy due to the risk of birth defects. It can cause hemolytic anemia, worsen pre-existing heart conditions, liver toxicity, respiratory symptoms (with inhalation therapy), psychiatric effects, and renal impairment. It can worsen conditions such as HBV co-infection, autoimmune disorders, eye disorders, thyroid dysfunction, and impaired fertility.
Ribavirin precautions include avoiding its use during pregnancy, monitoring for anemia, heart conditions, liver toxicity, respiratory symptoms, mental health changes, renal impairment, and considering HBV co-infection, autoimmune disorders, eye disorders, thyroid function, infertility, and drug interactions. Close collaboration with healthcare providers is vital for safe use.
Ribavirin can cause a range of side effects. Common side effects include fatigue, headache, nausea, insomnia, anemia, decreased appetite, muscle aches, irritability, and skin rash. Serious side effects may include hemolytic anemia, worsened heart conditions, liver toxicity, congenital disabilities if used during pregnancy, and respiratory symptoms with inhalation therapy.
Word Of Advice
It is crucial to prioritize safety when considering using Ribavirin or other medication. Avoid its use during pregnancy to protect the developing fetus. Use effective birth control during the treatment and at least six months after the last dose. Regularly monitor blood counts, liver function, and respiratory symptoms. Inform healthcare providers about pre-existing heart conditions, kidney impairment, and thyroid dysfunction. Be cautious of potential drug interactions and consider alternative treatments for co-existing conditions. Open communication with healthcare providers is vital for safe use. Prioritize your well-being by following these precautions and minimizing potential risks.
Frequently Asked Question
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Antiviral agents (Nonretroviral), 12th edition, 2011, 1613 - 1615.
- KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 804.
- Milpharm Limited, Electronic medicines compendium (EMC), [ Revised on Oct 2020] [ Accessed on 17th May 2023], https://www.medicines.org.uk/emc/files/pil.7108.pdf
- Merck Sharp & Dohme Corp., US Food and Drug Administration, [ Revised on Nov 2013] [ Accessed on 17th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020903s052,021546s008lbl.pdf
The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.