This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Rivaroxaban is an anticoagulant medication that was approved for medical use on 1st July 2011.

Mechanism of Action of undefined

Rivaroxaban Tablet is an anticoagulant medication belonging to the class of selective direct Factor Xa inhibitors. Rivaroxaban binds and forms a complex with Factor Xa.  Factor Xa is a natural substance in the body that is responsible for the formation of blood clots. Rivaroxaban is prescribed alone or in combination with low-dose aspirin.

Uses of undefined

Rivaroxaban Tablet has been developed to treat venous thromboembolism and its symptoms in adults and pediatric patients older than one month of age. It also prevents the occurrence of stroke, and blood clots in patients with acute critical illness, hospitalized patients, and in people with severe movement restriction. Rivaroxaban reduces the risk of a heart attack in patients diagnosed with coronary artery disease and atrial fibrillation.

undefined Drug administaration and Dosage available

Rivaroxaban is available as film-coated tablets in doses of 2.5mg, 10mg, 15mg, and 20mg. The accurate dose and frequency vary according to age and medical condition.

Warnings, Precautions and Side Effects of undefined

Warnings

Rivaroxaban Tablet is not recommended for patients with active bleeding, hypersensitivity, and a history of heparin-induced thrombocytopenia. Tell your physician before taking this Tablet if you are allergic to Rivaroxaban, heparin or its ingredients. Your healthcare provider will regularly monitor your blood count. Inform your healthcare practitioner if you are diagnosed with a spine, liver, or kidney problem. Get immediate medical attention if you experience back pain, tingling, numbness, muscle weakness, unusual bleeding or bruising, headache, or loss of bowel or bladder control (incontinence).

Precautions

Tell your healthcare provider if you are pregnant, breastfeeding or planning to have a baby. Rivaroxaban Tablet is probably unsafe during pregnancy as it may increase the risk of bleeding in unborn babies. Tell your doctor right away if you get pregnant during treatment with Rivaroxaban. This medicine has the tendency to pass into the breast milk. Discuss safe method of breastfeeding with your healthcare provider if you are planning to breastfeed your baby while on treatment with Rivaroxaban.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Rivaroxaban Tablet are bleeding, cough, vomiting, and inflammation in the gut and stomach. If you experience any allergic reactions after taking this medicine, report to your doctor immediately.

Word Of Advice

Rivaroxaban can cause bleeding and many undesirable side effects; hence it is advised to get adequate rest during the treatment. Avoid eating foods high in fats and calories. If you experience dizziness or any visual disturbances, you should avoid driving or handling machines. 

Frequently Asked Question

References

1. Janssen, [Revised on Jan 2022] [Accessed on 29th Sep 2022], https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/XARELTO-pi.pdf

2. KD Tripathi, Drugs Affecting Coagulation, Bleeding and Thrombosis, Essentials of Medical Pharmacology, 8th Edition, 2019, 659-681.

Disclaimer

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.