This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

The U.S. FDA approved Rocuronium bromide in 1994. Rocuronium bromide is  known as muscle relaxants. This medicine is used to induce muscle relaxation during surgeries and in intensive care units (ICU), used in procedures like tracheal tube insertion for artificial ventilation and short-term medical procedures requiring muscle relaxation. 

Mechanism of Action of undefined

Rocuronium bromide acts by blocking the signals between your nerves and muscles, competing with acetylcholine in your body. Acetylcholine normally connects with certain nicotinic cholinergic receptors to make muscles contract. But when this drug is around, it takes the place of acetylcholine, preventing muscle contractions. This happens because it stops the release of calcium ions, which are needed for muscle contraction. Thus, keeping your muscles relaxed.

Uses of undefined

Rocuronium bromide is used to induce muscle relaxation in tracheal tube insertion for artificial ventilation and in intensive care unit surgery (ICU).

undefined Drug administaration and Dosage available

This medicine is given only in a hospital setup by a healthcare provider. Rocuronium bromide will be given to you by your doctor. It is given intravenously (into a vein), either as single injections or as a continuous infusion (a drip). Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors. 

Warnings, Precautions and Side Effects of undefined


Individuals with allergies to the ingredients, kidney, liver, or gallbladder disease, heart or circulatory issues, fluid retention beneath the skin, nerve and muscle-related disorders, significant drops in body temperature, or a history of severe fever during anesthesia should be cautious when taking this medication. It is recommended to consult your doctor and monitor calcium, potassium, magnesium, protein, carbon dioxide, and acid levels before administration of the medicine.


It is not recommended for pediatric, pregnancy, and breastfeeding patients due to limited information without doctor advice. Consult your doctor if you are an overweight or older adult.Individuals with sudden weight loss and skin burning should inform their doctor before using the medicine. It may increase the heart rate of the children. So, it should be given by the doctor with proper monitoring of the heartbeat.

Side Effects

This medication can cause undesirable effects such as breathing difficulties or cessation, severe allergic coronary blood vessel spasms causing chest pain (angina) or heart attacks (myocardial infarctions), and pupil enlargement or unresponsiveness to light and stimuli.

Word Of Advice

Talk to your doctor if you have a disease affecting the nerves and muscles, such as polio (poliomyelitis), myasthenia gravis, or Eaton-Lambert syndrome and dehydration. Inform your doctor if you are under certain medicines which including certain antidepressants (MAOIs), heart disease or high blood pressure medications, diuretics, laxatives, quinine, epilepsy medications, corticosteroids, myasthenia gravis treatments, vitamin B1, azathioprine, theophylline, noradrenaline, potassium chloride, calcium chloride, and antiviral medications, it may potentially cause complications with rocuronium bromide.

Frequently Asked Question


  1. Dong-A ST Co. Ltd, WHO Public Assessment Reports (WHOPARs), [ Revised on September 2013] [Accessed on 25th Sep 2023],
  2. KD Tripathi, Essentials of Medical Pharmacology, Antitubercular drugs, 7th edition, 2013, 771.
  3. Goodman & Gilman’s, Chemotherapy of Tuberculosis, Mycobacterium avium complex disease, and Leprosy, 12th edition, 2011, 1562-1563.


The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.