This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Rosuvastatin + Clopidogrel is a lipid-lowering agent. Rosuvastatin belongs to the class of medications called HMG-CoA reductase inhibitors (Statins), and Clopidogrel belongs to the class of medications called thienopyridine derivatives. The FDA approved this combination to reduce high cholesterol in the body. It also helps to prevent heart attack and stroke.

Mechanism of Action of undefined

Rosuvastatin works by reducing the production of cholesterol in the body and lowering LDL (low-density lipoprotein) cholesterol levels. Clopidogrel prevents blood clot formation by inhibiting platelet aggregation. When used together, they help manage both cholesterol levels and the risk of blood clots.

Uses of undefined

It is used to reduce high cholesterol in the body. It also helps to prevent heart attack and stroke.

undefined Drug administaration and Dosage available

Your doctor will decide the dose and duration of Rosuvastatin + Clopidogrel based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time every day, with or without food. Do not break, chew, crush, or open the tablet. Swallow the whole tablet with water.

Warnings, Precautions and Side Effects of undefined


This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. Rosuvastatin + Clopidogrel should not be used if you have a known risk of bleeding, such as peptic ulcer, intracranial hemorrhage, or active bleeding disorders. The use of antiplatelet drug, in particular, can increase the risk of bleeding, so caution is required in individuals with bleeding tendencies.


Before starting the treatment, your doctor may perform liver function tests to evaluate your liver health. If you have a history of liver disease or experience any signs of liver issues (such as abdominal pain, dark urine, and yellowing of the skin or eyes), notify your doctor immediately. Rosuvastatin + Clopidogrel should be used with caution in individuals with impaired kidney function. Your doctor may need to adjust the dosage based on your kidney function and closely monitor your kidney health during treatment. This drug is not generally recommended during pregnancy or breastfeeding. It is necessary to consult this with your physician for more advice.

Side Effects

The common side effects of Rosuvastatin + Clopidogrel are headache, stomach pain, indigestion, heartburn, constipation, feeling sick, muscle pain and dizziness. Some serious side effects also include increased blood sugar levels, increased liver enzymes and liver injury , kidney problems , swelling in the, mouth or skin disorders (rashes and itching), difficulty in breathing, raised body temperature and enlarged lymph nodes.

Word Of Advice

Avoid exceeding the recommended dose or frequency of use unless your doctor advises. Before starting Rosuvastatin + Clopidogrel or any medication, inform your healthcare professional about any existing medical conditions, allergies, or medications you are taking for other issues. This detail will help them to decide if this tablet suits them and if any precautions or adjustments are necessary. Take this tablet after consulting your healthcare professional if you feel better. This tablet should be stored in a safe place, out of the reach of children. Accidental ingestion of this drug by children can be harmful.

Frequently Asked Question


  1. Pharmadox Healthcare Ltd, Electronic medicines compendium (EMC), [Revised on May 2023] [ Accessed on 19th June 2023],
  2. Mylan S.A.S, Electronic medicines compendium (EMC), [Revised on Feb 2020] [ Accessed on 19th June 2023],
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Drug therapy for hypercholesterolemia and dyslipidemia, 12th edition, 2011, 897.
  4. Bertram.G.Katzung, Basic and Clinical Pharmacology, Drugs Used in Disorders of Coagulation, 14th edition, 2017, 621.


The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.