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Written By
P. Thirumal Reddy
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)

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ROSUVASTATIN,CLOPIDOGREL
Last updated on 31 Mar 2026 | 09:30 AM (IST)
ROSUVASTATIN,CLOPIDOGREL
Background and Date of approval ROSUVASTATIN,CLOPIDOGREL
Rosuvastatin + Clopidogrel is a lipid-lowering agent. Rosuvastatin belongs to the class of medications called HMG-CoA reductase inhibitors (Statins), and Clopidogrel belongs to the class of medications called thienopyridine derivatives. The FDA approved this combination to reduce high cholesterol in the body. It also helps to prevent heart attack and stroke.
Uses of ROSUVASTATIN,CLOPIDOGREL
It is used to reduce high cholesterol in the body. It also helps to prevent heart attack and stroke.
How is ROSUVASTATIN,CLOPIDOGREL administered?
Your doctor will decide the dose and duration of Rosuvastatin + Clopidogrel based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time every day, with or without food. Do not break, chew, crush, or open the tablet. Swallow the whole tablet with water.
Side Effects of ROSUVASTATIN,CLOPIDOGREL
The common side effects of Rosuvastatin + Clopidogrel are headache, stomach pain, indigestion, heartburn, constipation, feeling sick, muscle pain and dizziness. Some serious side effects also include increased blood sugar levels, increased liver enzymes and liver injury , kidney problems , swelling in the, mouth or skin disorders (rashes and itching), difficulty in breathing, raised body temperature and enlarged lymph nodes.
Warnings
This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. Rosuvastatin + Clopidogrel should not be used if you have a known risk of bleeding, such as peptic ulcer, intracranial hemorrhage, or active bleeding disorders. The use of antiplatelet drug, in particular, can increase the risk of bleeding, so caution is required in individuals with bleeding tendencies.
Precautions
Before starting the treatment, your doctor may perform liver function tests to evaluate your liver health. If you have a history of liver disease or experience any signs of liver issues (such as abdominal pain, dark urine, and yellowing of the skin or eyes), notify your doctor immediately. Rosuvastatin + Clopidogrel should be used with caution in individuals with impaired kidney function. Your doctor may need to adjust the dosage based on your kidney function and closely monitor your kidney health during treatment. This drug is not generally recommended during pregnancy or breastfeeding. It is necessary to consult this with your physician for more advice.
Word of Advice
Avoid exceeding the recommended dose or frequency of use unless your doctor advises. Before starting Rosuvastatin + Clopidogrel or any medication, inform your healthcare professional about any existing medical conditions, allergies, or medications you are taking for other issues. This detail will help them to decide if this tablet suits them and if any precautions or adjustments are necessary. Take this tablet after consulting your healthcare professional if you feel better. This tablet should be stored in a safe place, out of the reach of children. Accidental ingestion of this drug by children can be harmful.
Frequently Asked Questions
Q1.
Can I drink alcohol while taking Rosuvastatin + Clopidogrel?
It is generally advised to limit alcohol consumption while taking Rosuvastatin + Clopidogrel. Excessive alcohol intake can cause certain side effects associated with these medications, such as liver function abnormalities.
Q2.
Is it necessary to follow a special diet while taking Rosuvastatin + Clopidogrel?
While taking Rosuvastatin + Clopidogrel, it is generally recommended to follow your cholesterol-lowering diet with exercises. A diet low in saturated fats can support the effectiveness of the medication in managing cholesterol levels. Your dietitian can provide specific dietary recommendations tailored to your needs.
Q3.
Can Rosuvastatin + Clopidogrel increase the risk of bleeding?
Yes, Rosuvastatin + Clopidogrel can increase the risk of bleeding in some individuals. This is primarily due to the antiplatelet effect of Clopidogrel, which inhibits platelet aggregation and can prolong bleeding time.
Q4.
How long should I take Rosuvastatin + Clopidogrel?
The duration of treatment with Rosuvastatin + Clopidogrel depends on your medical condition and individual factors. It is prescribed for the long-term management of conditions such as atherosclerosis or acute coronary syndrome. Follow your doctor's instructions regarding the duration of treatment and any necessary adjustments to the medication regimen.
Q5.
Can Rosuvastatin + Clopidogrel be taken at any time of the day?
Yes, Rosuvastatin + Clopidogrel can be taken at any time of the day. However, it is generally recommended to take it at the same time each day for better medication adherence. It can be taken with or without food, as directed by your healthcare provider.
References
- Pharmadox Healthcare Ltd, Electronic medicines compendium (EMC), [Revised on May 2023] [ Accessed on 19th June 2023],https://www.medicines.org.uk/emc/files/pil.13463.pdf
- Mylan S.A.S, Electronic medicines compendium (EMC), [Revised on Feb 2020] [ Accessed on 19th June 2023],https://www.medicines.org.uk/emc/files/pil.10075.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Drug therapy for hypercholesterolemia and dyslipidemia, 12th edition, 2011, 897.
- Bertram.G.Katzung, Basic and Clinical Pharmacology, Drugs Used in Disorders of Coagulation, 14th edition, 2017, 621.
Disclaimer
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.






