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Author Details

Written By
Sakshi Anil More
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)

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Quick Summary
S-ADENOSYL L- METHIONINE
Last updated on 31 Mar 2026 | 09:31 AM (IST)
S-ADENOSYL L- METHIONINE
Background and Date of approval S-ADENOSYL L- METHIONINE
Ademetionine/s-Adenosyl l-methionine is a nutritional and dietary supplement.
Uses of S-ADENOSYL L- METHIONINE
Ademetionine/s-Adenosyl l-methionine has been developed to treat intrahepatic cholestasis in pregnant women and adults with chronic liver disorders. S-adenosyl l methionine is also indicated to treat depression.
How is S-ADENOSYL L- METHIONINE administered?
Ademetionine/s-Adenosyl l-methionine is available in the form of 400mg tablets. The recommended dose is 400mg to 1200mg per day for 6 months.
Side Effects of S-ADENOSYL L- METHIONINE
Ademetionine/s-Adenosyl l-methionine is associated with side effects like rash, pruritus, muscle pain, fever, stomach pain, nausea, vomiting, headache and dizziness. If you experience any allergic or hypersensitivity reactions after taking this tablet, report to your physician immediately.
Warnings
During the Ademetionine/s-Adenosyl l-methionine treatment, your doctor may periodically monitor your blood parameters to prevent serious complications. Report to your doctor if you have been diagnosed with bipolar disorder, Parkinson’s disease, or problems in your lungs, heart or kidneys.
Precautions
There is no sufficient information about the impact of Ademetionine/s-Adenosyl l-methionine in breastfeeding women. Exercise caution before using Ademetionine/s-Adenosyl l-methionine if you are a breastfeeding mother.
Word of Advice
Eat a calorie-rich diet. Take Ademetionine/s-Adenosyl l-methionine only on your healthcare provider’s recommendation.
Frequently Asked Questions
Q1.
What is Ademetionine/s-Adenosyl l-methionine used for?
Ademetionine/s-Adenosyl l-methionine is a nutritional supplement indicated to improve symptoms in patients diagnosed with chronic liver disease.
Q2.
How long does it take for Ademetionine/s-Adenosyl l-methionine Tablet to work for depression?
It typically takes 4 to 6 weeks of consistent use to notice significant results of Ademetionine/s-Adenosyl l-methionine treatment.
Q3.
Who should not use Ademetionine/s-Adenosyl l-methionine?
People who are hypersensitive to Ademetionine/s-Adenosyl l-methionine, sulfa drugs or any of its excipients should not use Ademetionine/s-Adenosyl l-methionine.
Q4.
What are the side effects of Ademetionine/s-Adenosyl l-methionine?
Rash, pruritus, muscle pain, fever, stomach pain, nausea, vomiting, headache and dizziness are some of the most common side effects of Ademetionine/s-Adenosyl l-methionine.
Q5.
How do you store Ademetionine/s-Adenosyl l-methionine?
Store Ademetionine/s-Adenosyl l-methionine Tablets below 30˚C, away from the reach of children.
References
1. La Renon Healthcare Pvt Ltd., [Revised on Apr 2022] [Accessed on 30th Sep 2022], https://www.larenon.com/wp-content/uploads/2022/04/Cirrosam-LBL.pdf
2. Noureddin M, Sander-Struckmeier S, Mato JM. Early treatment efficacy of Sadenosylmethionine in patients with intrahepatic cholestasis: A systematic review. World J Hepatol 2020; 12(2): 46-63, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061266/pdf/WJH-12-46.pdf
Disclaimer
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.






