This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Ademetionine/s-Adenosyl l-methionine is a nutritional and dietary supplement.

Mechanism of Action of undefined

Ademetionine/s-Adenosyl l-methionine is a metabolic agent present in all living cells which plays an important role in several biochemical mechanisms. It is a direct metabolite of the amino acid L-methionine. Ademetionine undergoes methylation process and takes part in the synthesis of glutathione, a powerful antioxidant. This process decreases inflammation and protects the cells from damage.

Uses of undefined

Ademetionine/s-Adenosyl l-methionine has been developed to treat intrahepatic cholestasis in pregnant women and adults with chronic liver disorders. S-adenosyl l methionine is also indicated to treat depression.

undefined Drug administaration and Dosage available

Ademetionine/s-Adenosyl l-methionine is available in the form of 400mg tablets. The recommended dose is 400mg to 1200mg per day for 6 months.

Warnings, Precautions and Side Effects of undefined


During the Ademetionine/s-Adenosyl l-methionine treatment, your doctor may periodically monitor your blood parameters to prevent serious complications. Report to your doctor if you have been diagnosed with bipolar disorder, Parkinson’s disease, or problems in your lungs, heart or kidneys.


There is no sufficient information about the impact of Ademetionine/s-Adenosyl l-methionine in breastfeeding women. Exercise caution before using Ademetionine/s-Adenosyl l-methionine if you are a breastfeeding mother.

Side Effects

Ademetionine/s-Adenosyl l-methionine is associated with side effects like rash, pruritus, muscle pain, fever, stomach pain, nausea, vomiting, headache and dizziness. If you experience any allergic or hypersensitivity reactions after taking this tablet, report to your physician immediately.

Word Of Advice

Eat a calorie-rich diet. Take Ademetionine/s-Adenosyl l-methionine only on your healthcare provider’s recommendation.

Frequently Asked Question


1. Abott Laboratories, [Accessed on 30th Sep 2022],

2. La Renon Healthcare Pvt Ltd., [Revised on Apr 2022] [Accessed on 30th Sep 2022],

3. Noureddin M, Sander-Struckmeier S, Mato JM. Early treatment efficacy of Sadenosylmethionine in patients with intrahepatic cholestasis: A systematic review. World J Hepatol 2020; 12(2): 46-63,


The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.