This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Sodium Citrate contains an active component as Sodium Citrate. 

Mechanism of Action of undefined

By administering sodium citrate by injection, healthcare professionals can help neutralize the excess acid, restoring the body's pH balance and alleviating symptoms associated with acidosis, such as rapid breathing, confusion, and fatigue. By inhibiting the coagulation process, this medication ensures that the blood remains in a liquid state, facilitating the success of these procedures and reducing the risk of complications related to clot formation.

Uses of undefined

This medication is commonly used for various purposes, primarily in managing acidosis, as well as an anticoagulant for certain medical procedures.

undefined Drug administaration and Dosage available

To use sodium citrate, follow the instructions provided by your healthcare professional or as indicated on the product label. For the treatment of metabolic acidosis, this medication is typically administered intravenously under medical supervision. The dosage will be determined based on your specific condition and needs. For anticoagulant purposes during medical procedures, it is added to blood products to prevent clotting. 

Warnings, Precautions and Side Effects of undefined

Warnings

When using sodium citrate, several important warnings should be considered. This medication can cause severe allergic reactions. Allergic reactions can range from mild skin rashes to severe anaphylaxis, a life-threatening condition requiring immediate medical attention. Secondly, sodium citrate can affect the body's electrolyte balance, particularly levels of sodium and potassium. Additionally, this medication may interact with certain medications, especially those affecting the heart or electrolyte levels. 

Precautions

Firstly, individuals with known allergies to sodium citrate or any of its components should avoid using this medication. Therefore, caution is advised for individuals with kidney problems or conditions that may lead to electrolyte imbalances. It is crucial to inform your healthcare provider about all medications, supplements, or herbal products you are taking to prevent potential drug interactions. Pregnant and breastfeeding individuals should only use this medication under the guidance and supervision of a healthcare professional, as its safety during these periods has not been extensively studied. Be aware of the possibility of systemic absorption and withdrawal symptoms upon discontinuation. 

Side Effects

Sodium citrate, while generally well-tolerated, may cause some side effects. Common side effects include nausea, vomiting, diarrhea, abdominal discomfort, bloating, and excess gas (flatulence). In rare cases, individuals may experience allergic reactions, with symptoms like rash, itching, swelling, severe dizziness, or difficulty breathing, requiring immediate medical attention. Additionally, sodium citrate can impact electrolyte levels, potentially leading to imbalances such as low or high levels of sodium or potassium in the blood. This can result in symptoms like weakness, irregular heartbeat, muscle cramps, or seizures.

Word Of Advice

Advice regarding Sodium Citrate is to consult with a healthcare professional before starting or making any changes to your medication regimen. They can assess your medical history, evaluate potential risks and benefits, provide personalized guidance, and monitor your progress throughout treatment. Additionally, closely follow the instructions and recommendations your healthcare provider gives, promptly report any unusual or concerning symptoms, and communicate openly about any concerns or questions you may have. Precautions should be taken when using this medication in patients with liver or kidney impairment, as dosage adjustments or special monitoring may be required. Pregnant and breastfeeding individuals should consult with healthcare professionals before using this medication. Your healthcare professional is the best resource for ensuring safe and effective medication use. Special cautions are required in pediatrics and geriatrics.

Frequently Asked Question

References

  1. National Center for Biotechnology Information, PubChem Compound Summary for CID 6224, Sodium Citrate; [Published date: July 2023] [Accesses: 22/July/2023]; https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-citrate
  2. KD Tripathi, Essentials of Medical Pharmacology, Drugs affecting coagulation, bleeding and thrombosis, 7th edition, 2013, 617.
  3. La Renon Healthcare Pvt Ltd; [Accessed on 22/July/2023]; http://www.larenon.com/wp-content/uploads/2017/12/Serocit.pdf
  4. Terumo BCT, Inc, US Food and Drug Administration, [Issued on 2016] [Accessed on 22/July/2023], https://www.fda.gov/media/114460/download

Disclaimer

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.