This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Sodium valproate is an anticonvulsant drug developed by the U.S. Food And Drug Administration and initially approved in 1996 for treating epilepsy.

Mechanism of Action of undefined

Sodium valproate works by increasing the neurotransmitter levels called gamma-aminobutyric acid (GABA) in the brain. GABA helps to calm nerve activity and reduce the likelihood of seizures or mood swings.

Uses of undefined

Sodium valproate is used to treat epilepsy, including various seizure types and epilepsy syndromes. Epilepsy is a neurological disorder caused by recurrent and unpredictable seizures. Seizures are episodes of abnormal electrical activity in the brain that can lead to a wide range of symptoms, including loss of consciousness, muscle spasms, convulsions, altered sensations, or changes in behavior.  It can also be prescribed for neurological conditions like bipolar disorder and migraines.

undefined Drug administaration and Dosage available

Sodium valproate will be given to you by a doctor or other healthcare professional. It will be given as an intravenous injection (into a vein). It can also be given as an infusion through a drip into a vein. Your healthcare provider will decide the dose, route of administration, and duration of the treatment based on your health condition and other factors. Do not self-administer the medicine. 

Warnings, Precautions and Side Effects of undefined


Do not use Sodium valproate if you are allergic to Sodium valproate or any of the other ingredients of this medicine. Individuals with a rare condition called porphyria, which affects the breakdown of components of red blood cells, have a history of severe liver problems, urea cycle disorder, or mitochondrial disorder, such as Alpers-Huttenlocher syndrome. This medication should be avoided.


Before initiating the treatment, notify your physician if you have diabetes, kidney problems, brain disease, systemic lupus erythematosus, or a carnitine palmitoyltransferase type II deficiency. In these cases, discussing your medical history and conditions with your physician is necessary to ensure the safe and effective use of this injection. If you are a woman who can become pregnant and are taking Sodium Valproate, use an effective method of birth control throughout your entire treatment with this medication.

Side Effects

The side effects known to occur commonly during the treatment with Sodium valproate are diarrhea, stomach pain, nausea, vomiting, feeling dizzy or fainting, hearing problems, hair loss, changes in women’s periods, breast enlargement, swelling of feet and legs, weight gain, agitation, tingling or numbness in hands and feet, muscle pain and weakness. Some serious side effects include severe blistering rash, liver problems, blood clotting problems, mood changes, memory loss, and lack of concentration.

Word Of Advice

Alcohol can interact with Sodium valproate and potentially increase side effects like drowsiness. It's usually recommended to limit or avoid alcohol consumption while on this medication. Maintain a balanced diet and regular eating schedule. This medicine can affect appetite or cause weight gain, so it's important to discuss any dietary concerns with your doctor or a registered dietitian.

Frequently Asked Question


  1. Desitin Arzneimittel GmbH, Electronic medicines compendium (EMC), [Revised on Dec 2021] [ Accessed on 02 Sep 2023],
  2. Hospira, Inc, US Food and Drug Administration, [Revised on July 2013] [ Accessed on 02 Sep 2023],


The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.