Sucralfate + Metronidazole + Lignocaine belongs to the therapeutic class of anorectal preparation, hemorrhoid preparation, and anal fissure preparation. 

Sucralfate + Metronidazole + Lignocaine helps to heal the fissure and relieve the pain and inflammation. It can help to reduce the swelling and inflammation associated with hemorrhoids and fistulas.

Sucralfate + Metronidazole + Lignocaine is a topical medication that is applied directly to the skin. It is not for internal use. The choice of administration route may depend on the situation providing the medication.

The most common side effects of Sucralfate + Metronidazole + Lignocaine are burning, itching, stinging, redness, and rash. Serious side effects are rare, including allergic reaction, liver damage, seizures, peripheral neuropathy (nerve damage), and blood disorders.

Sucralfate + Metronidazole + Lignocaine can cause an allergic reaction, which can be mild or severe. Symptoms of an allergic reaction can include hives, swelling, difficulty breathing, and anaphylaxis. It can cause liver damage, especially if used for long periods. Symptoms of liver damage can include jaundice, nausea, vomiting, and abdominal pain.  It can cause peripheral neuropathy nerve damage in the hands and feet. Symptoms of peripheral neuropathy can include numbness, tingling, and pain in the hands and feet. It can cause blood disorders, such as anemia and thrombocytopenia.

If you experience any signs of an allergic reaction, stop using Sucralfate + Metronidazole + Lignocaine and contact your doctor immediately. If you experience these symptoms, stop using this medication and contact your doctor immediately.  If you have a history of blood disorders, diabetes, history of seizures, talk to your doctor before using this medication.

Do not use Sucralfate + Metronidazole + Lignocaine if you are allergic to it. Do not use this medication on broken or irritated skin. Do not use it inside the rectum. Avoid contact with the eyes, nose, and mouth. If you are pregnant or breastfeeding, talk to your doctor before using this medication. Use it exactly as prescribed by your doctor. Do not use more of the cream than prescribed. If you experience any side effects, stop using the cream and contact your doctor immediately. Be sure to tell your doctor about all the medications you are taking. It should be used cautiously in people with certain medical conditions, such as liver disease, lung disease, kidney disease, and neurological disorders. If you have any of these conditions, talk to your doctor before using it.

1. Banu karapolat; Could local antibiotics be included in the treatment of acute anal fissure?; Turkish Journal of Surgery; [Published on 1th Sept 2018][Accessed on 30th Sept 2023]; https://www.ncbi.nlm.nih.gov/pubmed/30248299
2. Pravin J Gupta et al.; Topical sucralfate treatment of anal fistulotomy wounds: a randomized placebo-controlled trial; Diseases of the Colon and Rectum; [Published on June 201][; Accessed on 30th Sept 2023]; https://pubmed.ncbi.nlm.nih.gov/21552054 /
3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Local Anaesthetics, 12th edition, 2011, 572- 573.
4. Pasquale Perrotti et al.; Topical nifedipine with lignocaine ointment vs. active control for the treatment of chronic anal fissure: results of a prospective, randomized, double-blind study; Diseases of the Colon and Rectum; [Published on Nov 2002][Accessed on 30th Sept 2023]; https://pubmed.ncbi.nlm.nih.gov/12432293/

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.