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TEICOPLANIN

TEICOPLANIN

Background and Date of approval TEICOPLANIN

Teicoplanin is an antibiotic that belongs to the class of medications called semisynthetic glycopeptide. The FDA approved this medicine for its use on 24 May 2018. FDA did not approve it for use in the USA. 

Uses of TEICOPLANIN

It is used in adults and children to treat bacterial infections of soft tissues, lungs, urinary tract, endocarditis, abdominal wall, blood, bones, and joints. It works by killing the bacteria that cause infections in the body.

How is TEICOPLANIN administered?

Teicoplanin is available as an injection. It will be given to you by a doctor or other healthcare professional. It will be given as an intravenous injection (into a vein) or intramuscular (into a muscle). It can also be given as an infusion through a drip into a vein. Your healthcare provider will decide the dose, route of administration, and duration of the treatment based on your health condition and other factors. Do not self-administer the medicine. 

Side Effects of TEICOPLANIN

The common side effects of teicoplanin are rash, pain, dizziness, fever, and diarrhea. Other serious side effects of this medicine are decreased platelet count, serious skin reactions, and renal failure.

Warnings

This drug is indicated to cause serious, life-threatening allergic reactions. Inform your physician immediately if you experience sudden allergic reactions such as difficulty breathing or wheezing, swelling, rash, itching, fever, and chills.  

Precautions

Do not use Teicoplanin if you are allergic to Teicoplanin or any of the other ingredients of this medicine. Inform your physician if you have flushing of the upper part of your body, a decrease in platelet count, kidney problems, and liver problems. Notify your doctor if you have allergic to an antibiotic called vancomycin. This medicine can cause serious rash or other skin symptoms. Inform your physician if you are pregnant or breastfeeding before initiating the treatment. 

Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications interact with teicoplanin and reduce their effectiveness by causing undesirable side effects.

Word of Advice

Store the teicoplanin below 30°C. Do not freeze. Protect the medicine from light and excessive moisture. Keep the medicine out of reach of children and pets. If you forgot to take the injection, inform your healthcare professional immediately and reschedule the appointment. 

Inform your physician if you have any unusual bleeding. Monitoring with regular kidney function tests may be needed while you are being treated with this medication. Inform your physician if you are pregnant or breastfeeding before starting the treatment. Store this medicine as per the package information. Do not stop taking this medicine without talking to your doctor.

Frequently Asked Questions

Q1.

Does teicoplanin cross the blood-brain barrier?

Teicoplanin shows a lower penetration rate into the blood-brain barrier than other glycopeptide antibiotics

Q2.

Is teicoplanin light-sensitive?

Teicoplanin should be stored away from direct light and excessive moisture. Excessive exposure can damage the efficacy of the medicine.

Q3.

Is teicoplanin safe during pregnancy?

Teicoplanin may be unsafe to use during pregnancy. Your doctor will decide whether to use this medicine or not. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment.

Q4.

Can teicoplanin be used in pediatric patients?

Teicoplanin can be used in pediatric patients, but the dosage and administration will be determined based on the child's weight, age, and specific indication.

Q5.

Are there any specific side effects associated with teicoplanin?

Common side effects of teicoplanin may include gastrointestinal disturbances (such as nausea, vomiting, and diarrhea), rash, dizziness, and decreased platelet counts. It is important to report any unusual or persistent side effects to your healthcare provider.

References

  1. Targocid 400mg powder for solution for injection/infusion or oral solution - Patient Information Leaflet (PIL) - (emc). www.medicines.org.uk. [revised 2022] [cited 2023 Jun 3]. Available from: https://www.medicines.org.uk/emc/product/2927/pil
  2. Camille E. Beauduy, Lisa G. Winston, Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 795-814.
  3. KD Tripathi, Macrolide, Lincosamide, Glycopeptide and other Antibacterial Antibiotics, Essentials of Medical Pharmacology, 8th Edition, 2019, 801-814.

Disclaimer

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.

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