This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Teicoplanin is an antibiotic that belongs to the class of medications called semisynthetic glycopeptide. The FDA approved this medicine for its use on 24 May 2018. FDA did not approve it for use in the USA. 

Mechanism of Action of undefined

The cell wall of gram-positive bacteria is entirely made of peptidoglycan, which is necessary for cell wall synthesis. Teicoplanin interferes with the cell-wall biosynthesis of bacteria by binding to specific residues and inhibiting the polymer membrane. It works by killing the bacteria which can cause serious infections.

Uses of undefined

It is used in adults and children to treat bacterial infections of soft tissues, lungs, urinary tract, endocarditis, abdominal wall, blood, bones, and joints. It works by killing the bacteria that cause infections in the body.

undefined Drug administaration and Dosage available

Teicoplanin is available as an injection. It will be given to you by a doctor or other healthcare professional. It will be given as an intravenous injection (into a vein) or intramuscular (into a muscle). It can also be given as an infusion through a drip into a vein. Your healthcare provider will decide the dose, route of administration, and duration of the treatment based on your health condition and other factors. Do not self-administer the medicine. 

Warnings, Precautions and Side Effects of undefined

Warnings

This drug is indicated to cause serious, life-threatening allergic reactions. Inform your physician immediately if you experience sudden allergic reactions such as difficulty breathing or wheezing, swelling, rash, itching, fever, and chills.  

Precautions

Do not use Teicoplanin if you are allergic to Teicoplanin or any of the other ingredients of this medicine. Inform your physician if you have flushing of the upper part of your body, a decrease in platelet count, kidney problems, and liver problems. Notify your doctor if you have allergic to an antibiotic called vancomycin. This medicine can cause serious rash or other skin symptoms. Inform your physician if you are pregnant or breastfeeding before initiating the treatment. 

Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications interact with teicoplanin and reduce their effectiveness by causing undesirable side effects.

Side Effects

The common side effects of teicoplanin are rash, pain, dizziness, fever, and diarrhea. Other serious side effects of this medicine are decreased platelet count, serious skin reactions, and renal failure.

Word Of Advice

Store the teicoplanin below 30°C. Do not freeze. Protect the medicine from light and excessive moisture. Keep the medicine out of reach of children and pets. If you forgot to take the injection, inform your healthcare professional immediately and reschedule the appointment. 

Inform your physician if you have any unusual bleeding. Monitoring with regular kidney function tests may be needed while you are being treated with this medication. Inform your physician if you are pregnant or breastfeeding before starting the treatment. Store this medicine as per the package information. Do not stop taking this medicine without talking to your doctor.

Frequently Asked Question

References

  1. Targocid 400mg powder for solution for injection/infusion or oral solution - Patient Information Leaflet (PIL) - (emc). www.medicines.org.uk. [revised 2022] [cited 2023 Jun 3]. Available from: https://www.medicines.org.uk/emc/product/2927/pil
  2. Camille E. Beauduy, Lisa G. Winston, Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 795-814.
  3. KD Tripathi, Macrolide, Lincosamide, Glycopeptide and other Antibacterial Antibiotics, Essentials of Medical Pharmacology, 8th Edition, 2019, 801-814.

Disclaimer

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.