This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Telmisartan + Azelnidipine is used to treat hypertension (high blood pressure). Telmisartan + Azelnidipine is an antihypertensive agent in the medication class known as an angiotensin II receptor antagonist. Angiotensin II is a naturally occurring substance that narrows your blood vessels, increasing blood pressure. Azelnidipine, a calcium channel blocker, also relaxes blood vessels, reducing pressure and improving blood flow.
Mechanism of Action of undefined
Telmisartan blocks angiotensin II receptors, while Azelnidipine inhibits calcium entry into smooth muscle cells, resulting in vasodilation and reducing peripheral resistance. This combined action effectively controls hypertension.
Uses of undefined
Telmisartan + Azelnidipine treats stage 2 hypertension (high blood pressure). It functions by inhibiting the effects of angiotensin II, causing the blood vessels to relax and decreasing blood pressure.
undefined Drug administaration and Dosage available
Take the Telmisartan + Azelnidipine tablet as your physician advises. Usually, it is taken once a day. Take medicine at a fixed time. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Warnings, Precautions and Side Effects of undefined
Warnings
Do not consume Telmisartan + Azelnidipine if you are allergic to Telmisartan, Azelnidipine, and its other ingredients. Also, do not consume if you have severe liver (biliary obstruction) conditions or combined with aliskiren-containing products in patients with diabetes mellitus or renal impairment. Before starting the treatment, inform your doctor if you have any liver, kidney, or heart conditions. Azelnidipine is contraindicated in women who may be pregnant or already pregnant, as well as in combination with certain medications like azole antifungals and HIV protease inhibitors.
Precautions
Avoid abrupt discontinuation of calcium antagonists. Your physician will monitor for excessive blood pressure decrease, hepatic function disorders, and jaundice and adjust the dose if needed. Also, your doctor will discontinue Telmisartan + Azelnidipine if abnormalities occur. Before starting the treatment, inform your doctor if you have a myocardial infarction, arrhythmia, or heart failure. Avoid consuming grapefruit juice while taking the medication.
Side Effects
The most common side effects of Telmisartan + Azelnidipine are low blood pressure, back pain, sinusitis, and diarrhea. Serious side effects while taking Telmisartan + Azelnidipine are sepsis (blood poisoning) and angioedema (swelling in the deeper layers of the skin).
Word Of Advice
Liver and heart patients should take Telmisartan + Azelnidipine cautiously and inform their doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double dose to make up for a forgotten dose. Notify your doctor if you experience any serious side effects.
Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information. Do not consume grapefruit or grapefruit juice. Keep out of sight and reach of pets and children. Do not freeze the medicine. Do not store above 25°C. Always check the expiry date before consuming it.
Frequently Asked Question
References
- Glenmark Pharmaceuticals Europe Limite., Electronic medicines compendium (emc), [Revised on November 2019] [ Accessed on 30th May 2023],13 Product Information (medicines.org.uk)
- Hetero labs limited, US Food and Drug Administration, [Revised on August 2015] [Accessed on 30th May 2023], 205901Orig1s000lbl.pdf (fda.gov)
- J. B. Chemicals & pharmaceuticals LTD, [Revised on November 2021] [ Accessed on 30th May 2023], *Azovas-T40-T80_PI_India_November-2021.pdf (jbpharma.com)
Disclaimer
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.
