This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Telmisartan+Chlorthalidone is a combination medication that contains two active ingredients, telmisartan, and chlorthalidone. This combination is primarily used to treat high blood pressure (hypertension). This makes it convenient for patients requiring an angiotensin II receptor blocker (ARB) and a diuretic for managing blood pressure. Instead of taking two pills, patients can take a single tablet, simplifying the medication regimen. Telmisartan belongs to a class of medications known as angiotensin II receptor blockers (ARBs). Chlorthalidone is a diuretic commonly called a "water pill." Telmisartan received FDA approval on October 28, 1998, and Chlorthalidone in 1988.

Mechanism of Action of undefined

The therapeutic effect of Telmisartan+Chlorthalidone tablets, a combination medication containing telmisartan and chlorthalidone, is the reduction of high blood pressure (hypertension) through dual mechanisms. Telmisartan works by blocking the action of angiotensin II, a hormone that constricts blood vessels, promoting vasodilation and relaxation of the blood vessels. Chlorthalidone, a diuretic, increases urine production, removing excess salt and water from the body, leading to decreased fluid volume in the blood vessels. Combining these two agents helps in lowering blood pressure, helping to protect against cardiovascular diseases, and providing kidney protection in certain cases.

Uses of undefined

Telmisartan+Chlorthalidone medicine used to treat hypertension, chronic kidney disease, and diabetic nephropathy (kidney condition caused by long-standing diabetes).

undefined Drug administaration and Dosage available

To use Telmisartan+Chlorthalidone tablets, follow your doctor's instructions precisely. Take the tablets orally with a glass of water, either with or without food. Taking the medication simultaneously daily is important to maintain a consistent routine. Do not adjust the dosage or stop taking the medication without consulting your healthcare professional.

Warnings, Precautions and Side Effects of undefined


Telmisartan+Chlorthalidone tablets carry several warnings. These include the potential for hypotension (low blood pressure), electrolyte imbalances, caution in individuals with renal or hepatic impairment, the risk of allergic reactions, contraindication during pregnancy and breastfeeding, the possibility of hyperkalemia (high potassium levels), increased risk of gout attacks, impact on blood glucose levels in diabetes.


When taking Chlorthalidone, exercise caution by informing your healthcare professional about existing medical conditions, monitoring blood pressure and electrolyte levels, using caution when operating machinery or driving, avoiding excessive sunlight exposure, staying hydrated, and seeking immediate medical attention for allergic reactions or severe side effects. Consult your healthcare professional for personalized advice.

Side Effects

Telmisartan+Chlorthalidone tablets may cause various side effects. Common side effects include dizziness, headache, fatigue, increased urination, muscle cramps or weakness, and low blood pressure symptoms such as feeling faint or lightheaded. Serious side effects can include allergic reactions, severe dizziness or lightheadedness, fainting, high potassium levels, and liver problems.

Word Of Advice

While taking Telmisartan+Chlorthalidone tablets, inform your healthcare professional about any existing medical conditions, including kidney or liver problems, diabetes, asthma, or gout, as dose adjustments or alternative treatments may be required. Regularly monitoring blood pressure, electrolyte levels, kidney function, and blood glucose levels is crucial. Staying hydrated and maintaining a balanced diet with adequate salt intake is advisable. If you experience any allergic reactions, difficulty breathing, swelling, or severe side effects, seek immediate medical attention. Finally, always consult your healthcare professional for personalized guidance and adhere to their recommendations throughout treatment.

Frequently Asked Question


  1. J Clin Diagn Res et al, The Antihypertensive Efficacy of Chlorthalidone and Telmisartan in Indian Hypertensive Patients who were Uncontrolled with Hydrochlorothiazide and Telmisartan Combination-A Prospective and an Open-Label Study, [Published on April 2013], [Accessed date 25 June 2023],
  2. HanAll BioPharma Co., Ltd., Pharmacokinetic Interactions and Safety Study of Telmisartan and Chlorthalidone, [Published on April 2013], [Accessed date 25 June 2023],


The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.