This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Telmisartan + Clinidipine + Chlorthalidone treats hypertension (high blood pressure). It  is an antihypertensive agent known as an angiotensin II receptor antagonist in the medication class. Angiotensin II is a naturally occurring substance that narrows your blood vessels, increasing blood pressure. Azelnidipine, a calcium channel blocker, also relaxes blood vessels, reducing pressure and improving blood flow. 

Mechanism of Action of undefined

It works by relaxing the blood vessels by blocking the angiotensin and making the heart pumping action efficient. Chlorthalidone removes the excess water and fluids from the body, relaxes the blood vessels, and improves the blood flow over time.

Uses of undefined

Telmisartan + Clinidipine + Chlorthalidone treats hypertension (high blood pressure). It functions by inhibiting the effects of angiotensin II, causing the blood vessels to relax and decreasing blood pressure. 

undefined Drug administaration and Dosage available

Take the Telmisartan + Clinidipine + Chlorthalidone tablet as your physician advises. Usually, it is taken once a day. Take medicine at a fixed time. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Warnings, Precautions and Side Effects of undefined

Warnings

Do not consume Telmisartan + Clinidipine + Chlorthalidone tablet if you are allergic to Telmisartan, Azelnidipine, and its other ingredients. Inform the doctor about kidney, diabetes, and liver-related problems and if you take other medicines for blood pressure and heart conditions. Telmisartan + Clinidipine + Chlorthalidone tablet is not recommended during early pregnancy and should not be taken beyond the first three months as it may harm the unborn baby. Report to your medical professional if you are pregnant or think you may be pregnant or planning for the pregnancy before starting the treatment.

Precautions

Telmisartan + Clinidipine + Chlorthalidone tablet should be used cautiously in liver patients. Before starting the treatment, inform your doctor about pre-existing liver conditions. Dose adjustment is needed in such conditions. Your physician will monitor for excessive blood pressure decrease, hepatic function disorders, and jaundice and adjust the dose if needed. Also, your doctor will discontinue Telmisartan + Clinidipine + Chlorthalidone if abnormalities occur.  It is unsafe to consume alcohol or handle a machine while taking Telmisartan + Clinidipine + Chlorthalidone tablet. Please speak with your physician.

Side Effects

The most common side effects of Telmisartan + Clinidipine + Chlorthalidone are glucose intolerance, irregular heartbeats, and palpitation. Serious side effects while taking Telmisartan + Clinidipine + Chlorthalidone are Fever Swelling in ankles, dizziness and tiredness, feeling sleepy, headaches, back pain, stomach upset, nausea Muscle pain. 

Word Of Advice

It is suggested to tell your doctor if you have any history of allergic reactions to avoid life-threatening complications. Tell the doctor before the treatment commencement if the patient is pregnant or having liver, kidney, or uterine problems and other medicines taken for hypertension and a heart condition. 

While using Telmisartan + Clinidipine + Chlorthalidone tablet, blood pressure, liver, and diabetes should be monitored regularly, and a kidney function test should be performed to note if there are any abnormal changes. As this medicine is a diuretic, it causes frequent urination; it's better to take this medicine 4 hrs before going to bed, and keeping the leg above the table in the raised position will reduce ankle swelling.

Frequently Asked Question

References

  1. KD. Tripathi. Antianginal and Other Anti-ischaemic Drugs & Drugs Affecting Renin-Angiotensin System. Eighth edition. June 2018. Page – 596 & 536.
  2. https://www.medicines.org.uk/emc/files/pil.9981.pdf (revised on November 2019) (accessed on 20th June 2023)
  3. https://pubchem.ncbi.nlm.nih.gov/compound/cilnidipine#section=Top (revised on 5/11/2022) (accessed on 20th June 2023)
  4. https://go.drugbank.com/drugs/DB00310 (revised on 8/11/2022) (accessed on 20th June 2023)

Disclaimer

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.