This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Telmisartan+metoprolol+ chlorthalidone contains the active constituents of telmisartan +metoprolol +chlorthalidone, which belong to the antihypertensive drugs which help in controlling high blood pressure and excess water and electrolyte from the body. Telmisartan+metoprolol+ chlorthalidone helps in relaxing the blood vessels by making the heart easier to pump blood all over the body, and it decreases the risk of heart attack and stroke. Telmisartan received FDA approval for the treatment of hypertension on July 21, 1998. Chlorthalidone received FDA approval for the treatment of hypertension on October 16, 1960. Metoprolol received FDA approval on August 18, 1992

Mechanism of Action of undefined

It works by relaxing the blood vessels by blocking the angiotensin and making the pumping action of the heart efficient. Chlorthalidone removes the excess water and fluids from the body and also relaxes the blood vessels, and improves the blood flow over some time.

Uses of undefined

Telmisartan+metoprolol+ chlorthalidone is used to treat hypertension.

undefined Drug administaration and Dosage available

This medication is taken as per the advice of the doctor. It can be taken on an empty stomach or along with food, but it has to be taken at a fixed time daily. It’s very important to take this medicine even if you feel well. As it causes frequent urination, it's better to have this tablet 4 hrs before going to bed. The dosage of this medication will depend upon the condition and how individuals respond to the medication. Avoid breaking or chewing the tablet. Instead, swallow it whole with a glass of water.

Warnings, Precautions and Side Effects of undefined

Warnings

These medications carry certain warnings and precautions. They should be used cautiously or avoided in individuals with allergies to any components, severe liver or kidney disease, certain heart conditions, or asthma. Chlorthalidone may increase blood sugar levels and requires caution in individuals with diabetes. 

Precautions

These medications can also interact with other drugs, so you must inform your healthcare provider about all the medications you are taking. Regular monitoring of blood pressure, electrolyte levels, and kidney and liver function may be necessary during treatment. It is recommended to consult with a healthcare professional for personalized guidance and to ensure safe and appropriate use of these medications.

Side Effects

The common side effects of telmisartan, metoprolol, and chlorthalidone may include dizziness, fatigue, headache, low blood pressure, increased urination, electrolyte imbalances (such as low potassium or sodium levels), and gastrointestinal disturbances like nausea or diarrhea. 

Word Of Advice

It is suggested to tell your doctor if you have any history of allergic reactions to avoid life-threatening complications. Tell the doctor before the treatment commencement if the patient is pregnant or having liver, kidney, or uterine problems and other medicines taken for hypertension and a heart condition. While using this medication, blood pressure, liver, and diabetes should be monitored regularly, and a kidney function test should be performed to note if there are any abnormal changes.

Frequently Asked Question

References

  1. KD. Tripathi. Antianginal and Other Anti-ischaemic Drugs & Drugs Affecting Renin-Angiotensin System. Eighth edition. June 2018. Page – 596 & 536.
  2. https://www.medicines.org.uk/emc/files/pil.9981.pdf [Revised on November 2019] [Accessed on 26/06/2023]
  3. https://go.drugbank.com/drugs/DB00310 [Revised on 8/11/2022) [Accessed on 26/06/2023]

Disclaimer

The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.