This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Tenofovir Alafenamide is an antiviral medication which was approved for its medical use on 10th November 2016.

Mechanism of Action of undefined

Tenofovir Alafenamide Tablet is a nucleoside analogue reverse transcriptase inhibitor that acts against hepatitis B virus. It works by inhibiting the reverse transcriptase enzyme of hepatitis B virus and HIV 1, interferes with the viral replication, lowers the amount of virus in your body and improves the condition of your liver.

Uses of undefined

Tenofovir Alafenamide Tablet has been developed to treat chronic hepatitis B virus infection in adults with compensated liver disease.

undefined Drug administaration and Dosage available

Tenofovir Alafenamide is available as a 25mg tablet. It is indicated once daily with food.

Warnings, Precautions and Side Effects of undefined


Contact your doctor immediately if you experience shortness of breath, loss of appetite or allergic reactions. Tenofovir Alafenamide is not recommended alone to treat HIV infection because of increased possibility for treatment resistance. Your healthcare provider will monitor you for the presence of HIV infection, liver disorder and kidney problems. Tell your healthcare provider if you have been diagnosed with problems in your heart, kidneys, liver or lungs.


Tenofovir Alafenamide is probably unsafe during pregnancy and breastfeeding. Do not take this medicine without your doctor's recommendation. Tell your healthcare provider before starting this treatment if you are pregnant, think you might be pregnant, breastfeeding, or planning to have a baby.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Tenofovir Alafenamide Tablet are headache, stomach pain, cough, back pain, fatigue, nausea, diarrhoea, dyspepsia, vomiting, rash and flatulence. If you experience any symptoms like unusual weakness, muscle pain, cold hands and feet, yellowing of skin and eyes, dark urine, loss of appetite and light-coloured stools, report to your doctor immediately.

Word Of Advice

Tenofovir Alafenamide has the tendency to make you feel dizzy. Hence, it is advisable to avoid driving and handling machines during this treatment. Tell your healthcare provider before taking this medicine if you have been diagnosed with lactose intolerance.

Frequently Asked Question


  1. Gilead Sciences, Inc., US Food & Drug Administration, [Revised on Sep 2021] [Accessed on 24th Aug 2022],
    1. Jennifer J. Kiser and Charles W. Flexner, Goodman & Gilman’s Pharmacological Basis of Therapeutics, Treatment of Viral Hepatitis (HBV/HCV), 13th Edition, 2018, 1119-1135.


The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.