This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Teriparatide is a synthetic agent which was approved for its medical use on 26th November 2002.

Mechanism of Action of undefined

Teriparatide Injection is a synthetic agent that acts as a substitute for parathyroid hormone. It is classified as an anabolic class of osteoporosis medications. The parathyroid hormone helps in the regulation of bone metabolism, reabsorption of calcium and phosphate by the kidneys and calcium by the intestine. Teriparatide Injection specifically binds to the surface receptors, improves skeletal mass, and stimulates new bone formation.

Uses of undefined

Teriparatide Injection has been developed to treat men and postmenopausal women with osteoporosis or at high risk for fracture who have not responded to other therapies.

undefined Drug administaration and Dosage available

Teriparatide Injection is available as a solution for Injection, cartridge, and pen in doses 600mcg, and 750mcg. It is indicated for administration through a subcutaneous route, into the thigh or abdominal wall. You can take this injection once daily with or without food.

Warnings, Precautions and Side Effects of undefined

Warnings

Teriparatide Injection is not recommended for patients with an increased risk of bone cancer, which includes people with hereditary bone disorders, skeletal malignancies, and Paget’s disease. It is also not recommended for patients with urolithiasis, orthostatic hypotension, and hypercalcemia. During the Teriparatide Injection treatment, your doctor may periodically monitor your blood and urine calcium, and kidney parameters to prevent serious complications. Report to your doctor if you have had a history of heart failure or bone disorders. Get immediate medical attention if you have breathlessness or allergies.

Precautions

Teriparatide Injection is not recommended for use during pregnancy and breastfeeding. Tell your healthcare provider before starting this treatment if you are pregnant, think you might be pregnant, breastfeeding, or planning to have a baby.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Teriparatide Injection are joint pain, nausea, headache, neck pain, hypertension, constipation, diarrhea, dyspepsia, vomiting, dizziness, depression, insomnia, vertigo, cough, rash, and sweating. If you experience any reactions like rashes, bruising, swelling, and itching at the Injection site, report them to your doctor immediately.

Word Of Advice

Teriparatide Injection can cause dizziness, headache and sickness. So it is advisable to avoid driving or handling machines during this treatment. Apply a cold compress at the Injection site to reduce the pain.

Frequently Asked Question

References

1. KD Tripathi, Hormones and Drugs Affecting Calcium Balance, Essentials of Medical Pharmacology, 8th Edition, 2019, 360-372.

2. Lilly USA, LLC, [Revised on Apr 2021] [Accessed on 23rd Aug 2022], https://pi.lilly.com/us/forteo-pi.pdf

3. Vall H, Parmar M., Teriparatide, [Updated 2022 Jul 12], In: StatPearls [Internet], [Accessed on 23rd Aug 2022], https://www.ncbi.nlm.nih.gov/books/NBK559248/ 

Disclaimer

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.