This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Thyroxine Sodium was approved by the U.S. FDA to treat hypothyroidism on 30 th November 2020.

Mechanism of Action of undefined

Thyroxine sodium is a synthetic form of thyroid hormone produced by the thyroid gland. It functions by replacing the thyroid hormones that your thyroid gland cannot generate sufficiently and relieves hypothyroidism symptoms like tiredness, weight gain, and depression.

Uses of undefined

Thyroxine Sodium has been approved to treat hypothyroidism (underactive thyroid gland).

undefined Drug administaration and Dosage available

The recommended starting dose for adults is 50- 100 micrograms every day. For patients over the age of 50, the suggested dose is 50 micrograms every day. Take Thyroxine sodium as prescribed by your doctor. It should be taken orally before breakfast or the first meal of the day. Swallow the tablets as a whole with plenty of water. Do not crush, break or chew the tablets.

Warnings, Precautions and Side Effects of undefined


Contact your physician immediately if you experience allergies to Thyroxine sodium and its ingredients. Let your healthcare provider know if you suffer from heart problems like angina, coronary artery disease, or high blood pressure. Inform your doctor if you have fits (epilepsy) or panhypopituitarism (hormonal disorder). When diabetes mellitus patients take this medication, their glycemic control may worsen, and they may need more insulin or antidiabetic medication. So, it is important to closely monitor blood glucose levels before starting, altering, or discontinuing thyroid hormone with Thyroxine sodium Tablet. Your physician decides the right dose of this medication after checking the body weight and thyroid function test. Regular monitoring of thyroid function is essential to ensure the effectiveness of the medication.


Consult your doctor before using Thyroxine sodium if you are pregnant or planning to have a baby. Your physician will decide if you should continue taking this medicine during pregnancy, particularly during the first three months. Avoid breastfeeding your baby while on the treatment, as it is unknown whether Thyroxine sodium passes into the breastmilk.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Thyroxine sodium are diarrhea, vomiting, weight loss, heat intolerance, headache, nervousness, irregular periods, sweating, muscle weakness or cramps, tremors, etc. Report to your healthcare provider immediately if you experience swelling of the face, lips, or tongue, Thyroid crisis (severe reaction to high levels of thyroid hormone), very high temperature, or palpitations (irregular heartbeat) to avoid severe complications.

Word Of Advice

You will be advised to take regular thyroid function tests (T3, T4, and TSH) if you take Thyroxine sodium. This medication is not indicated for obesity or weight loss treatment. Regular monitoring of blood sugar is advised by your physician, as this medicine causes blood sugar level fluctuations. Including iodized salt in your diet is essential because the thyroid gland requires iodine for making thyroid hormones.

Frequently Asked Question


  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Thyroid and Anti-thyroid drugs, 12th Edition, 2011, 1130-1150.
  2. Neolpharma, Inc; US Food & Drug Administration, [Revised on Dec 2017] [Accessed on 1 Nov 2022],
  3. Glenmark pharmaceuticals Europe Limited., Electronic medicines compendium (EMC), [Revised on April 2021] [Accessed on 1 Nov 2022],
  4., Accessed on 1 Nov 2022.


The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.