This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Ticagrelor is an antiplatelet medication developed by the U.S. Food And Drug Administration and initially approved on 20 July 2011, for treating acute coronary syndrome (ACS).
Mechanism of Action of undefined
Ticagrelor works by inhibiting platelet activation and aggregation. It specifically blocks a receptor called P2Y12 on the platelets, preventing them from clumping together and forming blood clots. This helps reduce the risk of heart-related events in individuals with ACS.
Uses of undefined
Ticagrelor is used to prevent blood clots in patients with acute coronary syndrome (ACS), including unstable angina or myocardial infarction (heart attack).
undefined Drug administaration and Dosage available
Ticagrelor is a prescription medicine available as a tablet in two doses, Ticagrelor 60mg and Ticagrelor 90mg. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Warnings, Precautions and Side Effects of undefined
Ticagrelor is contraindicated in individuals with known hypersensitivity or allergic reactions to other ingredients in it. If you are scheduled for surgery (including dental work), it is important to inform your doctor. Due to the increased risk of bleeding associated with this drug, your physician may advise you to stop taking the medication five days prior to the surgery. If you develop irregular breathing patterns such as speeding up, slowing down, or experiencing short pauses in breathing, it is recommended to consult your doctor for further evaluation.
Ticagrelor is not recommended during pregnancy or if there is a possibility of becoming pregnant. It is advised for women to use appropriate contraceptive measures to prevent pregnancy while using this medication. If you are breastfeeding, it's important to consult with your physician before taking this drug. This drug is not recommended for children and adults under 18 years of age.
The side effects known to occur commonly during the treatment with Ticagrelor are headache, indigestion, nausea, constipation, rash, itching, pain and swelling in the joints, blurred vision, bleeding gums, and bruising. Some serious side effects also include shortness of breath, blood clotting problem, fainting, and bleeding (red or black stools, coughing up or vomiting with blood, red, pink, or brown urine).
Word Of Advice
Since Ticagrelor affects platelet production, it's essential to take precautions to avoid injuries and bleeding. Be cautious when engaging in activities that may increase your risk of injury, and report any unusual bleeding or bruising to your physician.
Frequently Asked Question
- AstraZeneca UK Limited, Electronic medicines compendium (EMC), [ Revised on Aug 2022] [ Accessed on 17th July 2023], https://www.medicines.org.uk/emc/files/pil.5767.pdf
- Sohita Dhillon; Ticagrelor: a review of its use in adults with acute coronary syndromes; American Journal of Cardiovascular Drugs: drugs, devices and other interventions; Published on Feb 2015; Accessed on 17th July 2023; https://pubmed.ncbi.nlm.nih.gov/25672642/
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Blood coagulation and anticoagulant, fibrinolytic and antiplatelet drugs, 12th edition, 2011, 871.
The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.