Uses of undefined

Topiramate treats patients aged 2 years and older as initial monotherapy for partial-onset or primary generalised tonic-clonic seizures. It also provides adjunctive therapy for adults and pediatric patients aged 2 to 16 with these types of seizures and for those 2 years and older with Lennox-Gastaut syndrome. Topiramate also helps in preventing migraine headaches in adults.

undefined Drug administaration and Dosage available

Consult your healthcare provider for proper administration of topiramate. The dosage depends on your specific condition and individual needs. You can take topiramate before, during, or after a meal. Never stop taking topiramate without discussing it with your healthcare provider, as sudden withdrawal may cause serious problems. If you have epilepsy, stopping abruptly can lead to seizures that do not stop. Your healthcare provider will instruct you on how to taper off topiramate safely.

Warnings, Precautions and Side Effects of undefined

Warnings

Topiramate increases the risk of suicidal thoughts and behaviour, so closely monitor patients for any signs of these symptoms. It can harm unborn babies when administered to pregnant women, particularly increasing the risk of oral clefts in exposed infants. Be vigilant for hyperammonemia, especially when using topiramate in combination with valproic acid, as this can lead to encephalopathy. Additionally, ensure that patients stay hydrated to reduce the risk of kidney stones associated with the medication.

Precautions

• Cognitive/Neuropsychiatric effects: Monitor for signs of cognitive dysfunction and psychiatric disturbances; consider dose adjustments or discontinuation if needed.
• Withdrawal of AEDs: Gradually withdraw antiepileptic drugs to minimise the risk of seizures.
• Renal and hepatic impairment: Adjust the dosage for patients with renal or hepatic impairment; exercise caution.
• Metabolic acidosis: Regularly monitor serum bicarbonate levels due to the risk of non-anion gap and hyperchloremic metabolic acidosis.
• Drug interactions: Assess for potential interactions with other medications.
• Pediatric use: Monitor pediatric patients closely. Although they may have a lower incidence of adverse reactions, vigilance is still essential.

Side Effects

Common Side Effects:

• Tingling or numbness
• Weight loss
• Loss of appetite
• Drowsiness
• Difficulty with memory
• Fatigue
• Confusion
• Dizziness

Rare Side Effects:

• Acute myopia
• Decreased sweating and hyperthermia
• Metabolic acidosis
• Cognitive/neuropsychiatric reactions
• Hyperammonemia and encephalopathy (with or without valproic acid)
• Kidney stones
• Hypothermia (with concomitant valproic acid)

Word Of Advice

Tell your doctor if you have a history of heart failure. Monitor your blood glucose levels regularly to prevent hypoglycemia while using linagliptin. Report any symptoms of low blood sugar without delay. Inform your doctor about all other medications you take to avoid potential interactions. Use linagliptin during pregnancy only when necessary. Watch for allergic reactions and report any issues right away.

Frequently Asked Question

• What is topiramate mainly used for?
• Topiramate is mainly used to prevent migraines and to treat epilepsy. It helps reduce the frequency of seizures and migraine attacks. It can also be prescribed for certain mood disorders.

• Will I gain weight if I stop topiramate?
• If you stop topiramate, you may gain weight, as the medication can suppress appetite. Some people experience weight loss as a side effect while on topiramate. However, weight changes vary by person and depend on factors like diet and lifestyle. Always consult your healthcare provider for guidance when considering changes to your medication.

• Can you take topiramate every day?
• Yes, you can take topiramate every day as prescribed by your healthcare provider. It is often taken daily to help control seizures or prevent migraines. Always follow your doctor’s instructions regarding dosage and frequency.

• Is topiramate an antidepressant?
• No, topiramate is not an antidepressant. It is an antiepileptic medication primarily used to treat seizures and prevent migraines.

• Who can't take topiramate?
• Topiramate is not suitable for everyone. Tell your doctor if you have a history of allergic reactions to it, kidney problems, acute porphyria, metabolic acidosis, glaucoma, or liver issues. If you are pregnant or trying to conceive, enrol in a pregnancy prevention program before starting topiramate. Always consult your healthcare provider for personalised advice.