This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Trastuzumab is a monoclonal antibody that was approved for its medical use on 25th September 1998.

Mechanism of Action of undefined

Trastuzumab Injection is a biological agent that acts as targeted drug therapy in cancer treatment. It is classified as a monoclonal antibody belonging to the class a HER2/neu receptor antagonists. HER2 or human epidermal growth factor receptor 2 is a protein present in high concentrations on the surface of cancer cells of the breast and gastric region. Trastuzumab Injection works by binding with these receptors, ultimately inhibiting the growth of cancer cells.

Uses of undefined

Trastuzumab Injection has been developed to treat solid tumors by injecting it as an intravenous infusion. Trastuzumab Injection has been approved to treat HER2 overexpressing breast cancer and stomach cancer (gastro-oesophageal Junction adenocarcinoma).

undefined Drug administaration and Dosage available

Trastuzumab is available as multi dose vial injections in the doses 150 mg and 440 mg. It is intended for intravenous infusion only and not for IV push or bolus.

Warnings, Precautions and Side Effects of undefined


Contact your doctor immediately if you experience breathlessness, fever, or infection. During the Trastuzumab injection treatment, your doctor may periodically monitor your blood cell counts, platelets, blood sugar, electrolytes and kidney parameters to prevent serious complications. Report to your doctor if you have had a history of heart failure. Do not substitute trastuzumab with Ado- trastuzumab emtansine. Beware of chemotherapy-induced neutropenia (low white blood cells) during this treatment. Get immediate medical attention if you experience sudden shortness of breath, cough, swelling of the ankles, palpitations, weight gain, dizziness or loss of consciousness.


For female patients of reproductive potential, the healthcare provider will conduct a pregnancy test prior to initiating this treatment. Inform your healthcare provider if you are pregnant, breastfeeding, or you became pregnant within seven months of completing Trastuzumab treatment course. Discuss effective contraceptive methods to use during treatment and for 7 months following the last dose of Trastuzumab Injection.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Trastuzumab Injection are headache, nausea, diarrhea, chills, fever, infection, insomnia, cough, rash, tiredness, anemia, weight loss, upper respiratory tract infection.

Word Of Advice

Trastuzumab can make you feel tired and dizzy, so you should avoid driving or handling machines. Apply cool compress to avoid injection site reactions. 

Frequently Asked Question


1. Genentech, Inc., US Food & Drug Administration, [Revised on Feb 2021] [Accessed on 29th Aug 2022],

2. Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.


The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.