This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Trimoxazole is an antibiotic medication developed by the U.S. Food And Drug Administration and initially approved for treating bacterial infections.

Mechanism of Action of undefined

Trimoxazole treats and prevents bacterial infections in children up to 12 years of age. It is also helpful in treating certain types of urinary tract infections, respiratory tract infections, middle ear infections, bronchitis, and pneumonia.

Uses of undefined

Trimoxazole acts by inhibiting the synthesis of folic acid, an essential nutrient that bacteria need for the production of nucleic acids and proteins. By blocking the folic acid synthesis pathway, this drug interferes with the disruption of the growth and multiplication of bacteria.

undefined Drug administaration and Dosage available

Always take Trimoxazole as instructed by your doctor. This medicine should be taken orally. Your doctor will decide the dose and duration of the treatment based on the disease condition and other factors. Do not overdose on the medicine. 

Warnings, Precautions and Side Effects of undefined


This drug is contraindicated in individuals with known hypersensitivity or allergic reactions to other sulfonamide medicines, such as sulfonylureas or thiazide diuretics. Your child should not take this medicine if they have a porphyria condition because this drug affects the skin or nervous system. Diarrhea is a common side effect associated with the use of antibiotics. If your child develops watery or bloody stools, it is recommended to contact your physician immediately. Jolltrim 50ml Oral Suspension should not be given to infants during the first six weeks from the day they are born. This restriction is likely due to safety concerns or insufficient evidence regarding its use in young infants.


Before administering Jolltrim 50ml Oral Suspension, it is important to inform your physician if your child has any pre-existing liver disorders, kidney disorders, blood disorders, allergic conditions, intolerance to sugars, or any other diseases. This information is necessary as it helps the physician to assess the suitability of the medication for your child and determine the appropriate dosage. Notify your physician if you are pregnant, breastfeeding, or planning to have a baby.

Side Effects

The side effects known to occur commonly during the treatment with Trimoxazole are headache, feeling sick (nausea), diarrhea., skin rashes and candidiasis. Some serious side effects also include difficulty in breathing, fainting, swelling of the face, mouth, tongue, or throat may be red and painful and cause difficulty in swallowing, chest pain, and red patches on the skin.

Word Of Advice

It is essential to complete the entire course of treatment as prescribed by the healthcare professional. Skipping doses or not finishing the full course may reduce the effectiveness of the medication and increase the risk of antibiotic resistance. Avoid skipping the medicine. Take a dose as soon as you remember. Do not take an extra dose to make up for a missed dose. Shake this medicine well before use. 

Frequently Asked Question


  1. Aspen Pharma Trading Limited, Electronic medicines compendium (EMC), [Revised on July 2021] [Accessed on 13th July 2023]
  2. KD Tripathi, Essentials of Medical Pharmacology, Sulfonamides, Cotrimoxazole, and Quinolones, 7th edition, 2013, 706-708.
  3. Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for urinary tract infections, 12th edition, 2011, 1468-1470.


The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.