This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Triptorelin is a gonadotropin releasing hormone agonist which was approved for its medical use on 15th June 2000.

Mechanism of Action of undefined

Triptorelin is a gonadotropin-releasing hormone agonist that binds to the gonadotropin receptors of the pituitary gland. It lowers the androgen and testosterone levels in men and estrogen levels in women. It is prescribed in combination with androgen antagonists like flutamide or bicalutamide to prevent the initial flare-up of the tumor.

Uses of undefined

Triptorelin Injection is an anticancer medication indicated for the palliative treatment of advanced prostate cancer.

undefined Drug administaration and Dosage available

Triptorelin is available as a vial for injection in doses of 3.75mg, 11.25mg, and 22.5mg.  It is administered as an intramuscular injection into either of the buttocks. 

Warnings, Precautions and Side Effects of undefined


Triptorelin Injection is not recommended for people who are hypersensitive to Triptorelin or other GnRH agonists. Your healthcare provider will monitor your serum testosterone levels, blood glucose levels and cardiac function. Regular monitoring will prevent the risk of spinal cord compression and urinary tract obstruction. Tell your healthcare provider if you have been diagnosed with heart problems or diabetes.


Triptorelin can impair fertility in men and women of reproductive age. Triptorelin is not recommended for use during pregnancy as it has the tendency to cause fetal harm. Hence, it is advisable to tell your physician before starting this treatment if you are pregnant or planning to get pregnant. It is not known if Triptorelin passes into breast milk. If you are a breastfeeding mother, your healthcare provider will suggest whether to discontinue breastfeeding or discontinue this treatment based on your condition.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Triptorelin Injection are hot flashes, skeletal pain, impotence, headache, swelling of legs, leg pain, diarrhea, vomiting, dizziness, hypertension, insomnia, pruritus, and urinary tract infection.

Word Of Advice

Triptorelin can cause urinary tract infections. Hence, it is advised to consume plenty of water during the treatment and reach out to your healthcare provider if you experience discomfort. 

Frequently Asked Question


1. Verity Pharmaceuticals Inc., [Revised on Oct 2020] [Accessed on 26th Aug 2022],

2. KD Tripathi, Essentials of Medical Pharmacology, Anterior Pituitary Hormones, 8th Edition, 2019, 257-266.

3. Claudine Isaacs, Anton Wellstein, and Anna T. Riegel, Hormones and Related Agents in the Therapy of Cancer, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1237-1247.


The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.