Trospium chloride was initially approved by the United States Food and Drug Administration (FDA) in 2004.

Trospium chloride is an antimuscarinic medication used to treat the symptoms of an overactive bladder (OAB). This medication reduces the frequency and urgency of urination and improves bladder control. It is also used in conditions like irritable bowel syndrome (IBS) and chronic constipation.

Trospium chloride is available in two routes of administration: oral and extended-release oral. The oral form is a tablet taken orally, with or without food, twice a day. The extended-release oral form is a capsule taken by mouth once daily, usually in the morning. The choice of route of administration will depend on the individual patient's needs and preferences.

The most common side effects of trospium chloride include dry mouth, constipation, blurred vision, difficulty urinating, headache, and dizziness. This medication can also cause more serious side effects, such as urinary retention, glaucoma, myasthenia gravis, and allergic reactions.

Trospium chloride can cause dry mouth, leading to tooth decay, gum disease, and other dental problems. It can also cause constipation. If you experience constipation, talk to your doctor about ways to relieve it. It can make it difficult to urinate. This medication can worsen glaucoma.

It is important to brush your teeth and floss regularly and use fluoride toothpaste if you are taking Trospium chloride. If you experience constipation, talk to your doctor about ways to relieve it. If you experience difficulty urinating, stop taking this medication and seek medical attention immediately. If you have glaucoma, talk to your doctor before taking it.

Take Trospium chloride with food to reduce the risk of side effects, such as dry mouth. Before taking this medication, it is important to talk to your doctor about all your medications, including over-the-counter and herbal supplements. You should also tell your doctor if you have any conditions like glaucoma, myasthenia gravis, heart disease, liver disease, kidney disease, constipation, blurred vision, or dry mouth. If you are pregnant or breastfeeding, talk to your doctor about the risks and benefits of taking this medication. Be careful when driving or operating machinery while taking this medication, and do not drink alcohol. If you experience any side effects, talk to your doctor right away.

1. Glenmark Pharmaceuticals Europe Ltd, Electronic Medicines Compendium (EMC), [Revised on 10 Jun 2021] [Accessed on 11th September 2023], https://www.medicines.org.uk/emc/product/9883/pil#gref
2. J. Goddard, A.N. Turner, Kidney and urinary tract disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 461-523.
3. Joan Heller Brown, Katharina Brandl, and Jürgen Wess, Muscarinic Receptor Agonists and Antagonists, Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13th Edition, 2018, 149-161.
4. Allergan, Inc. US Food and Drug Administration, [Revised on 7th 2012]  [ Accessed on 11th September 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021595s009lbl.pdf

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.