Meloto spray is used to treat the following:

• Insomnia
• Jet lag
• Shift work sleep disorder
• Delayed sleep phase disorder
• Non-24-Hour sleep-wake disorder
• Sleep disturbances in children with autism
• Sleep disturbances in the elderly
• Sleep disturbances in ADHD

Meloto spray's mechanism of action centers on its role in regulating the circadian rhythm, where it is produced in response to decreasing light levels, inducing drowsiness and signaling the body's readiness for sleep. It also influences body temperature and hormone release and possesses antioxidant properties. It's impact extends to various bodily systems through its receptors. Still, its primary function remains in synchronizing the sleep-wake cycle, making it a key factor in managing sleep-related issues.

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Meloto spray, reducing effectiveness by causing undesirable side effects. 

• Store at room temperature, between 59°F to 77°F (15°C to 25°C)
• Keep away from moisture, heat, and light.
• It should not be frozen.
• Keep away from children and pets.

Meloto spray is typically taken orally. To use the melatonin oral spray, spray the suggested dose into your mouth under your tongue or inside your cheek. Hold for 30 seconds or a minute maximum before swallowing to absorb it into your system. It's important to follow the dosing instructions provided on the product's packaging or as your healthcare provider recommends. 

Meloto spray cause some side effects like all medications, although not everyone will experience them. 

Serious:

• Allergic reactions
• Hypotension (low blood pressure)
• Seizures
• Interactions with medications

Common:

• Daytime drowsiness
• Headache
• Stomach upset
• Mood changes
• Sleep-wake cycle disruption
• Hormonal effects

Consult a healthcare provider before use, especially if pregnant, breastfeeding, or with underlying health conditions; adhere to recommended dosages and timings, particularly for short-term use; be mindful of potential allergic reactions, drug interactions, and drowsiness when driving or operating machinery; avoid alcohol while taking Meloto spray; prioritize age-appropriate dosing for older adults, children, and adolescents; recognize individual sensitivity and adjust dosing if necessary; ensure proper evaluation of underlying sleep disorders before use; consult a healthcare provider if dealing with hormone-sensitive conditions, cancer, or other health concerns; be aware of potential withdrawal or dependency with long-term use; consider light sensitivity and promote a sleep-conducive environment; stay informed about potential interactions with other sleep aids or medications; tailor usage to your health profile and explore non-pharmacological sleep improvement strategies alongside this medication Always prioritize professional guidance for safe and effective use of this medication.

1. Elena Benelli et al.; A Combined Therapy with Myo-Inositol and D-Chiro-Inositol Improves Endocrine Parameters and Insulin Resistance in PCOS Young Overweight Women; Published on 14/07/2016; Accessed on 11/08/2023; https://www.ncbi.nlm.nih.gov/pubmed/27493664
2. Colonis Pharma Ltd, Electronic medicines compendium (EMC), [Revised on 05 Oct 2021] [ Accessed on 10th August 2023],https://www.medicines.org.uk/emc/product/10405/smpc#gref