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Zerofos 667mg Tablet_101707
Zerofos 667mg Tablet_101707 (2)
Zerofos 667mg Tablet_101707
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Zerofos 667mg Tablet

Salt Composition : Calcium Acetate


Origin of Medicine : India

MRP: 42
Price :37
You Save :5 (12%)

10 Tablet(s) In A Strip

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Introduction to Zerofos 667mg Tablet

Zerofos 667mg tablet contains active components such as Calcium acetate. It is a medication commonly used to manage high phosphate levels in the blood, known as hyperphosphatemia. It is primarily used in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) undergoing dialysis. It helps to maintain better bone health and reduce the risk of bone fractures and other bone-related issues. Zerofos 667mg tablet may reduce the risk of cardiovascular problems such as heart disease and calcification of blood vessels. It can be used as an adjunct to dietary modifications, improving the ability to control phosphate levels effectively. High phosphate levels can contribute to symptoms like itching and skin irritation, common in individuals with kidney disease. Lowering phosphate levels with it may provide relief from these symptoms.

If you experience hypersensitivity or an allergic reaction to the Zerofos 667mg tablet or any of its components, it is important to avoid this medication. Patients with severe kidney impairment or impairment of calcium metabolism should avoid this medication. Caution should be exercised in individuals with a history of kidney stones or kidney disease and those taking medications containing Calcium or magnesium. It is generally not recommended for use in children due to insufficient clinical data in pediatric populations. In older individuals, the use of this medication should be approached with caution because in older age, so many health problems present, such as they may have an increased risk of various health conditions, including impaired kidney function, cardiovascular issues, and calcium-related disorders. It is always important to consult a healthcare professional before starting this medication in old age.

Uses of Zerofos 667mg Tablet

Zerofos 667mg tablet is used in the following:

  • Hyperphosphatemia in CKD/ESRD
  • Adjunct to dietary management in CKD/ESRD dialysis

Therapeutic Effects of Zerofos 667mg Tablet

Zerofos 667mg tablet's therapeutic action is its ability to bind with dietary phosphate in the gastrointestinal tract. Upon ingestion, it dissociates into calcium and acetate ions. The calcium ions form insoluble complexes with phosphate ions from ingested foods, forming calcium phosphate salts that are not absorbed into the bloodstream. As a result, phosphate absorption from the diet is reduced, leading to lower phosphate levels in the blood. 

Interaction of Zerofos 667mg Tablet with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Zerofos 667mg tablet, reducing effectiveness by causing undesirable side effects. 

More Information about Zerofos 667mg Tablet

  • Should be stored at room temperature, between 20°C to 25°C.
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Zerofos 667mg Tablet

Zerofos 667mg tablet is typically administered orally, meaning it is taken by mouth as tablets or capsules. The medication is designed to be swallowed with water and should not be chewed or crushed unless specifically instructed by a healthcare provider. The oral route is the most common and effective way to use this medication to manage hyperphosphatemia in individuals with chronic kidney and end-stage renal disease.

Safety Advices for Zerofos 667mg Tablet

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Pregnant women should consult their healthcare provider before taking Zerofos 667mg tablet as its safety is not well studied in pregnant women. 

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Breast Feeding


Zerofos 667mg tablet's safety during breastfeeding is not well established. Consult a healthcare provider before using this medication while breastfeeding. 

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If you have lung conditions, it is advisable to consult your healthcare provider before using Zerofos 667mg tablet.

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Individuals with liver disease should consult a doctor regarding using Zerofos 667mg tablet with their healthcare provider, as there may be considerations related to calcium and phosphate metabolism.

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It is unsafe to use alcohol with Zerofos 667mg tablet as interaction can cause certain side effects and also reduces the efficacy of this medication. If you experience dizziness or nausea, it is unsafe to take Zerofos 667mg tablet with alcohol.

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If you are experiencing side effects that could affect your ability to drive or operate machinery safely, taking a Zerofos 667mg tablet while driving is unsafe.

Side Effects of Zerofos 667mg Tablet

Zerofos 667mg tablet causes some side effects like all medications, although not everyone will experience them. 


  • Hypercalcemia
  • Calcium-based tissue deposition
  • Aluminum toxicity


  • Upset stomach
  • Constipation
  • Abdominal pain
  • Loss of appetite
  • Itching
  • Hypocalcemia

Word of Advice

Inform your healthcare provider about your complete medical history, allergies, and ongoing medications or supplements to ensure safe usage. Regular monitoring of blood phosphate levels is important to assess the effectiveness of the Zerofos 667mg tablet in managing hyperphosphatemia. Stick to dietary recommendations your healthcare provider provides to complement the medication's effects. Be vigilant for symptoms of hypercalcemia, such as nausea, vomiting, and confusion, as well as symptoms of hypocalcemia. If you experience any adverse effects, consult your healthcare provider, who may adjust the dosage or recommend alternative treatments. Pregnant and breastfeeding individuals should seek guidance from a healthcare provider before using this medication. Discuss your allergies, history of hypersensitivity reactions, or underlying conditions like liver or lung issues with your healthcare provider before starting them. Always consult your healthcare provider for personalized advice and guidance on the safe and effective use of this medication in your specific circumstances.


Q 1. What should I do if I miss a dose of Zerofos 667mg tablet?

If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double up on doses.

Q 2. How long does it take for Zerofos 667mg tablet to work?

The time it takes for the Zerofos 667mg tablet to start lowering phosphate levels can vary. Your healthcare provider will monitor your blood levels and adjust the treatment plan as needed to achieve the desired results.

Q 3. What should I do if I experience adverse effects from the Zerofos 667mg tablet?

If you experience any adverse effects while taking Zerofos 667mg tablet, contact your healthcare provider. They can assess the situation, provide guidance, and adjust your treatment plan if necessary.

Q 4. How often should I monitor my blood levels while on the Zerofos 667mg tablet?

The frequency of blood tests will be determined by your healthcare provider. Regular monitoring is important to ensure that calcium and phosphate levels are within the appropriate range.

Q 5. Are there any long-term effects of using the Zerofos 667mg tablet?

Long-term use of Zerofos 667mg tablet may lead to calcium-based tissue deposition and other complications. Regular monitoring and follow-up with your healthcare provider can help manage potential long-term effects.

Q 6. Can Zerofos 667mg tablet lead to vitamin deficiencies?

Zerofos 667mg tablet's primary impact is on phosphate and calcium levels. However, it's important to discuss your nutritional needs and possible vitamin deficiencies with your healthcare provider.

Fact Box of Zerofos 667mg Tablet

Molecule name: Calcium acetate

Therapeutic class: Phosphate Binder

Pharmacological class: Calcium Salt, Phosphate Binder


1. Hyperphosphatemia in CKD/ESRD 

2.Adjunct to dietary management in CKD/ESRD dialysis


  1. RenaCare NephroMed GmbH, Electronic Medicines Compendium (EMC), [Revised on Feb 2012] [Accessed on 22 August 2023],
  2. Genzyme Ireland Ltd, US Food and Drug Administration, [Revised on: 04/2020 ] [Accessed on 23rd August 2023] ,,022318s021lbl.pdf
  3. J. Goddard, A.N. Turner, Kidney and Urinary Tract Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 461-523.


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