ACCENTRIX 2.3MG INJECTION

Introduction:

Accentrix 2.3mg Injection contains the active constituent ranibizumab. It is used to treat eye diseases causing impaired vision. It is used to treat Neovascular (Wet) Age-Related Macular Degeneration (a disease that can blur the center of the vision when abnormal blood vessels grow in the wrong place in your eye), and Macular Edema Following Retinal Vein Occlusion (occurs when the blood vessel in the eye becomes blocked).

It is used to treat Diabetic Macular Edema (occurs when excess fluid builds up in the part of the eye, which helps us focus and see fine details). Accentrix 2.3mg Injection is not recommended for adolescents and children under the age of 18. Use effective birth control during the treatment and for at least 3 months after the last dose. Talk to your doctor if you have any diseases, allergic conditions or if you had any previous eye treatments before starting treatment with this medication.

It is important to tell your doctor if you experience any symptoms such as eye pain, worsening eye redness, decreased or blurred vision, and increased insensitivity to light while being treated with Accentrix 2.3mg Injection. 

Uses of Accentrix 2.3mg Injection:

• Neovascular (wet) age-related macular degeneration (wet AMD)
• Impaired vision caused by diabetic macular edema (DME)
• Macular Edema Following Retinal Vein Occlusion (RVO)

How Accentrix 2.3mg Injection works:

A protein called VEGF-A (human vascular endothelial growth factor) in excess can cause the growth of abnormal blood vessels and swelling in the eye that can lead to the above-said diseases. Ranibizumab blocks the action of VEGA-A protein and helps improve vision. 

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

• Keep Accentrix 2.3mg Injection out of sight and reach of children. 
• Store in refrigerator 2° to 8°C. Do not freeze.

References:

1. Novartis Europharm Limited, Electronic medicines compendium (emc), [ Revised on Dec 2019] [ Accessed on 30th March 2022], https://www.medicines.org.uk/emc/files/pil.307.pdf 
2. Genentech, Inc, US Food and Drug Administration, [ Revised on Oct 2014] [ Accessed on 30th March 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/125156s105lbl.pdf   
3. James E Frampton; Ranibizumab: a review of its use in the treatment of neovascular age-related macular degeneration; Drugs & Aging; Published on May 2013; Accessed on 30/03/2022; https://pubmed.ncbi.nlm.nih.gov/23539234/
    

How to use Accentrix 2.3mg Injection:

It will be given to you by a physician experienced in giving eye injections. 

Safety advice:

Pregnancy:

This medicine should not be used in pregnant patients unless the benefits outweigh the risks. It will be given to you only if clearly needed.

Breastfeeding:

Inform your doctor if you are breastfeeding before taking this medicine. It will be given to you only if clearly needed.

Driving: 

Do not drive or handle heavy machines until the vision has recovered sufficiently. Consult your doctor before engaging in such acts while you are treated with this medicine. 

Others:

• Inform your doctor if you have an allergic condition or other diseases.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious:

• Tear or detachment of the layer in the back of the eye

Common:

• Inflammation of the eye
• Bleeding in the back of the eye
• Visual disturbances
• Eye pain, discomfort
• Floaters
• Eye irritation
• Increased tear production
• Dry eye
• Sore throat
• Nasal congestion
• Runny nose
• Headache
• Joint pain
• Infection
• A feeling of having something in the eye