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Adcetris 50mg Injection
Salt Composition : Brentuximab Vedotin
Manufacturer : TAKEDA PHARMACEUTICALS INDIA PVT LTD
Origin of Medicine : India
Introduction to Adcetris 50mg Injection
Adcetris 50mg injection is an anticancer medication that belongs to the CD30 monoclonal antibodies category containing the active ingredient Brentuximab vedotin. This medication is used to treat certain types of cancer, including classical Hodgkin lymphoma (cancer of the lymphatic system), cutaneous T-cell lymphoma (a type of non-Hodgkin lymphoma that affects the skin), and systemic anaplastic large-cell lymphoma (abnormal growth of T-lymphocytes). This drug is an antibody-drug conjugate (ADC) that targets cancer cells specifically. It may be used as a frontline treatment or when other treatments are ineffective.
Adcetris 50mg injection is contraindicated in individuals with known hypersensitivity or allergy to it or its component. Inform your physician if you have any pre-existing medical conditions of liver, kidney, or heart disease. Your doctor will perform regular blood tests to ensure the safety of receiving this medicine and to monitor for any serious adverse effects. Infusion site reactions can happen during treatment, including wheezing, difficulty breathing, hives, itching, or swelling. These symptoms require immediate medical attention.
If you and your partner are undergoing treatment with this drug, it is advised to use two effective methods of contraception during the treatment period. This is to prevent pregnancy while taking the medication. Women are advised to continue using contraception for an additional 6 months after the last dose of this injection. This extended period helps ensure that the medication is completely cleared from the body before attempting to conceive. Adcetris 50mg injection can cause fetal harm to the fetus when administered to pregnant women. Consult your doctor if you are pregnant, breastfeeding, or planning for pregnancy during the treatment.
Uses of Adcetris 50mg Injection
- Treatment of Hodgkin lymphoma
- Cutaneous T-cell lymphoma
- Systemic Anaplastic Large Cell Lymphoma
Therapeutic Effects of Adcetris 50mg Injection
Adcetris 50mg injection consists of an antibody that targets CD30, a protein found on the surface of cancer cells, and a chemotherapy drug that is attached to the antibody. The antibody delivers the chemotherapy directly to the cancer cells, minimizing damage to healthy cells.
Interaction of Adcetris 50mg Injection with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications such as anticonvulsants, digoxin, thiazide diuretics, cholestyramine, and antacids may interact with Adcetris 50mg injection and reduce effectiveness by causing undesirable side effects.
More Information about Adcetris 50mg Injection
- Store Brentuximab vedotin in a refrigerator (2 °C - 8 °C).
- Do not freeze.
How to consume Adcetris 50mg Injection
Adcetris 50mg injection can be administered only as an intravenous injection into a vein by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.
Safety Advices for Adcetris 50mg Injection
Adcetris 50mg injection can cause fetal harm to the fetus when administered to pregnant women. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
If breastfeeding, consult your doctor before starting the treatment with Adcetris 50mg injection.
It is unknown whether Adcetris 50mg injection is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.
Adcetris 50mg injection should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary. Inform your doctor if you have liver issues before initiating the therapy.
It is unknown whether consuming alcohol interacts with the Adcetris 50mg injection. Please consult your doctor for more advice.
Adcetris 50mg injection may be less likely to impair your ability to drive or operate machinery. Consult your doctor for more advice.
Side Effects of Adcetris 50mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Allergic reaction
- Infusion site reactions
- Memory loss
- Shortness of breath
- Inflammation of pancreas
- Blurred vision
- Loss of balance
- Decreased level of white blood cells
- Upper respiratory tract infection
- Decrease in weight
- Abdominal pain
- Muscle pain
- Swollen joints
Word of Advice
During the course of treatment with Adcetris 50mg injection and for a specified period afterward (up to 6 months following the last dose), men are advised not to father a child. This precaution is taken to minimize any serious risks to the unborn child that may arise from exposure to the medication.
Q 1. What cancers is Adcetris 50mg injection used to treat?
Adcetris 50mg injection is primarily used to treat classical Hodgkin lymphoma and systemic anaplastic large-cell lymphoma. It may be used as a frontline treatment or when other treatments have not been effective.
Q 2. How is Adcetris 50mg injection administered?
Adcetris 50mg injection is administered as an intravenous (IV) infusion by a physician in a clinical setting, such as a hospital or clinic.
Q 3. What precautions should I take before starting Adcetris 50mg injection?
Inform your physician about your medical history, current medications, and any allergies. Regular monitoring of blood counts and other relevant parameters may be necessary during treatment.
Q 4. Can I drive or operate heavy machinery while on Adcetris 50mg injection?
Adcetris 50mg injection may cause fatigue or other side effects that could affect your ability to drive or operate machinery. It's advisable to avoid such activities if you experience these effects.
Q 5. What are the common side effects of Adcetris 50mg injection?
Common side effects of Adcetris 50mg injection may include fatigue, nausea, diarrhea, fever, muscle pain, swollen joints and upper respiratory tract infections.
Fact Box of Adcetris 50mg Injection
Molecule name: Brentuximab vedotin
Therapeutic class: Anti-cancer
Pharmacological class: CD30 monoclonal antibodies
1. Treatment of Hodgkin lymphoma
2. Cutaneous T-cell lymphoma
3. Systemic Anaplastic Large Cell Lymphoma
- Takeda Pharma A/S, Electronic Medicines Compendium (EMC), [Revised on June 2022] [Accessed on 11 August 2023], https://www.medicines.org.uk/emc/files/pil.2859.pdf
- Brentuximab vedotin. Macmillan Cancer Support, [Revised on 1 July 2022], [Accessed on 11 August 2023], www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/brentuximab
- Adcetris, INN- brentuximab vedotin. [Revised on 10 Jan 2023], [Accessed on 11 August 2023], www.ema.europa.eu/en/documents/product-information/www.ema.europa.eu/en/documents/product-information/adcetris-epar-product-information_en.pdf
- Seattle Genetics, Inc. US Food & Drug Administration. [Revised Nov 2014], [Accessed on 11 August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/125388_s056s078lbl.pdf
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