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ALPHANATE 250IU INJECTION 5ML_200135_1
ALPHANATE 250IU INJECTION 5ML_200135_2
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ALPHANATE 250IU INJECTION 5ML_200135_1
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Alphanate 250IU Injection 5ml

Prescription Required

Salt Composition : Factor Viii

Manufacturer : GRIFOLS

Origin of Medicine : India

MRP: ₹3910.32
Price : ₹3450
You Save : ₹460 (12%)

1 Vial(s) Of 5ml

Introduction to Alphanate 250iu Injection 5ml

Alphanate 250IU Injection 5ml is an antihemophilic medicine in the class of miscellaneous coagulation modifiers containing the active ingredient Factor VIII. It is used to treat and prevent bleeding in individuals with hemophilia A, a genetic disorder caused by a deficiency or dysfunction of factor VIII, a clotting protein in the blood.

This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. Stop taking this tablet and contact your doctor immediately if you develop a rash or skin symptoms. The use of this drug increases the cardiovascular risk. It is highly advised to discuss with your physician if you have any existing heart disease condition before initiating the treatment with Alphanate 250IU Injection 5ml. A central venous access device (CVAD) may sometimes be required to administer this drug treatment. It's important to consider the risks associated with CVAD-related complications, including local infections, bacteremia (bacterial infection in the bloodstream), and catheter site thrombosis (blood clot formation at the catheter site). Proper care and monitoring should be exercised to minimize these risks. 

The development of inhibitors (antibodies) is a known complication that can occur during treatment with this medicine. These inhibitors can interfere with the effectiveness of the treatment. Patients receiving Alphanate 250IU Injection 5ml therapy should be closely monitored for the development of inhibitors. If bleeding is uncontrolled with this drug, you must notify your doctor immediately. If you are pregnant or breastfeeding, consult your doctor for more advice before starting the treatment with this drug.

Uses of Alphanate 250iu Injection 5ml

  • Treatment of Hemophilia A

Therapeutic Effects of Alphanate 250iu Injection 5ml

By facilitating the clotting process, Alphanate 250IU Injection 5ml helps prevent and control bleeding episodes in individuals with hemophilia A and other conditions associated with low factor VIII levels. It reduces the chance of complications such as bleeding, excessive blood loss, and related health issues.

Interaction of Alphanate 250iu Injection 5ml with other drugs

Inform your physician about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Alphanate 250IU Injection 5ml and cause undesirable side effects.

More Information about Alphanate 250iu Injection 5ml

  • Store Alphanate 250IU Injection 5ml in the refrigerator at (2°C to 8°C).
  • Do not freeze.

How to consume Alphanate 250iu Injection 5ml

Alphanate 250IU Injection 5ml is usually administered through a vein (intravenously) by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Do not self-administer this injection.

Safety Advices for Alphanate 250iu Injection 5ml

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Pregnancy

  

If you are pregnant, suspecting, or planning for the pregnancy, ask your doctor for more advice before starting the treatment with Alphanate 250IU Injection 5ml. 

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Breast Feeding

  

If breastfeeding, consult your doctor before starting the treatment with Alphanate 250IU Injection 5ml.

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Lungs

  

It is unknown whether Alphanate 250IU Injection 5ml is safe for patients with lung problems. Notify your doctor if you have lung disease before starting the treatment.

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Liver

  

It is unknown whether Alphanate 250IU Injection 5ml is safe for patients with liver problems. Inform your doctor if you have the liver disease before starting the treatment.

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Alcohol

  

It is unknown whether consuming alcohol while taking Alphanate 250IU Injection 5ml is safe. Please speak with your physician.

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Driving

  

Alphanate 250IU Injection 5ml does not affect your ability to drive and operate heavy machinery. Inform your physician if you face any symptoms that alter your concentration.

Side Effects of Alphanate 250iu Injection 5ml

Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them.

Serious

  • Allergic reaction (anaphylactic shock) or a hypersensitivity reaction

Common

  • Reddening of the skin
  • Burning and stinging at the injection site
  • Chills
  • Flushing
  • Headache
  • Hives
  • Hypotension
  • Lethargy
  • Nausea
  • Restlessness
  • Tachycardia
  • Tightness of the chest
  • Tingling
  • Vomiting
  • Wheezing

Word of Advice

If you regularly or repeatedly receive human plasma-derived Alphanate 250IU Injection 5ml products, your doctor may recommend vaccination against hepatitis A and B. It is because there is a possible risk of exposure to these viruses through plasma-derived products. Vaccination can help protect against these infections. 

Good dental hygiene is important to maintain oral health and prevent tooth and gum disease. It is particularly relevant for individuals with bleeding disorders such as hemophilia A, as they may be more susceptible to excessive bleeding. If you notice any changes in your symptoms or have concerns about the treatment with Alphanate 250IU Injection 5ml, immediately communicate them to your physician for more advice.

FAQs

Q 1. Is Alphanate 250IU Injection 5ml derived from human plasma or produced through recombinant DNA technology?

Alphanate 250IU Injection 5ml can be derived from human plasma, which undergoes a purification process or is produced using recombinant DNA technology.

Q 2. Can Alphanate 250IU Injection 5ml be used in children?

Yes, Alphanate 250IU Injection 5ml can be used in children. The dosage and administration may vary based on the child's age, weight, and needs. Pediatric patients with hemophilia A can benefit from regular treatment with this drug to prevent and manage bleeding episodes.

Q 3. Are there any potential side effects of Alphanate 250IU Injection 5ml?

The most common side effect of Alphanate 250IU Injection 5ml is the development of inhibitors (antibodies) that can interfere with the effectiveness of the treatment. Other possible side effects include allergic reactions, infusion site reactions, and the risk of blood clots.

Q 4. How is Alphanate 250IU Injection 5ml administered?

Alphanate 250IU Injection 5ml is administered intravenously (IV) through a needle inserted into a vein by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Q 5. Can Alphanate 250IU Injection 5ml be used during surgery or dental procedures?

Alphanate 250IU Injection 5ml can be used before surgery or dental procedures in individuals with hemophilia A to prevent excessive bleeding. Coordinating with the healthcare team is important to ensure proper dosing and timing.

Fact Box of Alphanate 250iu Injection 5ml

Molecule Name: Factor VIII 

Therapeutic class:  Antihemophilic agents

Pharmacological class: Miscellaneous coagulation modifiers

Indications: Treatment of Hemophilia A

References

  1. Biotest Pharma GmbH, Electronic Medicines Compendium (EMC), [Revised on Dec 2022], [Accessed on 01 July 2023], Available at: https://www.medicines.org.uk/emc/files/pil.579.pdf.
  2. Baxter Healthcare Corporation- food and drug administration (FDA), [Accessed on 01 July 2023] Available at: https://www.fda.gov/media/78280/download#:~:text=Factor%20VIII%20is%20the%20specific,spontaneously%20or%20after%20minor%20trauma.
  3. KD Tripathi, Essentials of Medical Pharmacology, Drugs affecting coagulation, bleeding, and thrombosis, 7th edition, 2013, 217.

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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